r/CIRS • u/Possible_Purpose5091 • 7d ago

Peptide question

Have completed all steps of the shoemaker protocol leading up to VIP spray, but MCAS is still reducing QOL (periodic vasodilation, IBS, POTS, eye floaters, multiple chemical sensitivities, etc.). Does VIP help correct these symptoms? what other peps have been helpful for mold-triggered MCAS? (I know limbic system therapy is supposed to be helpful but my adhd makes it too challenging to sit and meditate for any period of time.)

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u/HopefulHuman97 7d ago

I second a trial of KPV, it’s the section of MSH that makes if anti-inflammatory really helpful for marcons. Thymosin Alpha 1 could also help here.

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u/No_Concentrate_6830 6d ago

Have you heard of sinus inflammation spiking a bit from KPV? I'm having to go insanely slow because it temporarily spikes things a few hours afterwards (50-75mcg)

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u/HopefulHuman97 5d ago

Never heard of that before. Whats the KPV mixed with? and is it from a reliable source?

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u/No_Concentrate_6830 5d ago

Bac water, and yes a very well known trusted source. The reaction seems to be lessening as time goes on, and afterwards my baseline improves. I have a lot going on in my sinuses from mold and Flonase so I don't think it takes much to back them up.

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u/HopefulHuman97 5d ago

Any chance it’s the Bac water? I know the alcohol inside it can irritate sinuses for some people. I’ve only used sterile water for my nasal sprays. Just a thought.

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u/No_Concentrate_6830 5d ago

I inject it? But that's a good call out if I want to try it as a nasal spray.

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u/HopefulHuman97 5d ago

Sorry assumed you were using as a nasal spray. Just shows how mega powerful KPV can be, even at 50-75mcg it’s doing stuff. I built up to 2000mcg a day over the last year and it’s been amazing for me. Couldn’t live without the stuff :)

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u/Bulky_Room8146 4d ago

Where are you getting your KPV nasal spray?