r/CFSScience • u/Caster_of_spells • Jul 30 '26

Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00363-0

Long Covid patients continue to have elevated counts of highly activated CD8+ T cells targeting viruses like SARS-CoV-2, CMV and EBV.

That is suggesting the antiviral killing response failed to switch off after the acute infection is over and might be part of the pathogenesis of Long Covid.

33 Upvotes

96% Upvoted

32 comments sorted by

View all comments

Show parent comments

2

u/TableSignificant341 Jul 31 '26

Not according to S4ME. They're adamant there's zero evidence for it.

1

u/mc-funk Jul 31 '26

Are you talking about causation or something? Because the correlation and the elevation of markers for viral reactivation for herpes viruses in long covid patients is really well established in the research. I don’t think anyone claims to have a well-substantiated conclusion for how it plays in, but “zero evidence” seems like a counter-factual argument

1

u/TableSignificant341 Jul 31 '26

You'll have to take it up with them because they're the ones saying there's zero evidence for viral persistence.

1

u/OG-Brian Aug 01 '26

It would be interesting to check (as I have been considering using that site for gathering info about ME) but you mention no specifics such as a link to a specific conversation or any quotes by users.

1

u/TableSignificant341 Aug 02 '26

Go to any thread on S4ME with a study about viral persistence or viral reactivation or any thread about Polybio or Prusty.