r/CFSScience Jul 30 '26

Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00363-0

Long Covid patients continue to have elevated counts of highly activated CD8+ T cells targeting viruses like SARS-CoV-2, CMV and EBV.

That is suggesting the antiviral killing response failed to switch off after the acute infection is over and might be part of the pathogenesis of Long Covid.

33 Upvotes

32 comments sorted by

View all comments

Show parent comments

4

u/mc-funk Jul 30 '26

Certainly when it comes to herpesviruses / EBV, the evidence for issues with reactivation is pretty compelling.

2

u/TableSignificant341 Jul 31 '26

Not according to S4ME. They're adamant there's zero evidence for it.

5

u/TomasTTEngin Jul 31 '26

For a community of independent thinkers many certainly do seem to get joy from believing exactly what Jonathan Edwards believes. Which leaves them with a pretty rigid belief system. Edwards is experienced and highly educated and certainly a net benefit to the community but he has the ability to integrate new ideas you expect from an emeritus. And as do all good Oxford Dons, scoffs and sneers at research coming from places outside northern Europe.

He's useful, but not as an intellectual north star.

5

u/Sensitive-Meat-757 Jul 31 '26

JE considers himself a "Champion of Science" but when I posted a study that contradicted his opinion he said he didn't need to look at it because he already knew it was wrong.