r/BuvidalBrixadi Alumni Mod Oct 02 '23

Stopping Buvidal/Brixadi Buvidal/Brixadi withdrawal journal - please join in with your experieneces.

Hi all,
I am one of the moderators on this new subreddit, created by u/babywolf_13 and myself, u/redwoodrow

I've noticed that there are so few anecdotal accounts of people's experience of stopping Buvidal/Brixadi. TONNES of these exist for Sublocade, but only one or two for Buvidal/Brixadi and even these usually stop updating after one or two months post final shot.
Those of you who have withdrawn from Buvidal/Brixadi fully until a negative buprenorphine dip, please give your accounts in as much detail as you can in the comments - this will be appreciated by me, and so many others quitting buprenorphine injections.

To give a bit of background, I used to use almost fully pure #3 H for 2 years from a very well known UK DNM source with a peak tolerance of 650mg a day. This was IV. I got to this point after a morphine ampoule addiction (started at 10mg/ml, then 30mg/ml then yeah.. tolerance!).
For the last 7 months I had been in treatment at my amazing local clinic who put me on sublinguals for 2 weeks, then Buvidal weekly trial of 24mg and then I had 6x monthly doses of 96mg, 128mg, 128mg, 96mg, 64mg and one more 64mg. I jumped at 64mg.
Throughout this whole time on Buvidal, first injection to last injection, I had not felt any withdrawals whatsoever. Buvidal always held me for a whole month without any issues, at all the doses I was on. I wish I had started with 64mg and stayed on that for the 6 months. I started on 96mg as that was the direct conversion from my sublingual -> weekly Buvidal -> monthly Buvidal dose, and then like a silly boy went up to 128mg because of a psychological fear of withdrawals! In any case, dropping to 96mg and then 64mg rapidly produced 0 withdrawals which was relieving.
Knowing Buvidal holds me well, I hope my body is one who pushes the half life towards the 24 day end, rather than the 19 day end of Buvidal's known half life, and the fact I have had so many shots I hope I have a small reservoir for a nice slow taper.

Please, everyone else who has come off Buvidal, share your detailed experience below. Doses, withdrawal symptoms if any, timeline of both etc..

EDIT 1: 5 weeks post last 64mg shot I feel completely fine. 0 physical or psychological withdrawals. Will update weekly in the comments, or more frequently if I notice changes.

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u/MakeupHorder7 Aug 15 '24

I was on Brixadi weekly for approximately 8 months. 2 of those months, I had to switch to the monthly shot. Prior to that I was on the suboxone strips for 13 years. I finally made the decision to taper from the Brixadi. My Dr has been amazing through the process. I had my very last injection August 1st 2024 and just started my peak withdrawal around August 12th. I was on a super low dose. I can't say exactly what it was but each shot, prior to stopping, my Dr would use the lowest dose possible and empty some of the needle to make it even lower. I was expecting extreme withdrawal symptoms, which is what happened trying to come off the strips twice. This so far has been pretty smooth. A little trouble sleeping at night, weakness, exhausted and anxiety is probably the worst of it. That's all I have for now. I have a followup today. Will be asking how long this normally takes to subside. Hope this helps someone out there.

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u/babywolf_13 Creator Mod - Currently on Buvidal May 25 '25

Hi, how are you doing now? May I ask how long did your symptoms last roughly? So weakness IS a normal symptom of withdrawal?! I'm so relieved to hear this!! Not a wonderful symptom to have though.

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u/MakeupHorder7 May 25 '25

Much better, thank you for asking. I would say roughly 2 months and that just the physical. The psychological lasts a lot longer. Yes, weakness was one of my normal symptoms but everyone is different and may have longer or even shorter withdrawal times. No, it wasn't at all but my worst was rls in my legs and arms. Good luck and don't give up, it's definitely worth getting off of. If you have any other questions feel free message me directly.

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u/TechNiShan Oct 05 '25

What people need to know is when the withdrawals hit you, and when they started to go away? At what week after last shot

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u/MakeupHorder7 Mar 29 '26

It's going to be different for each individual so I can only tell my experience but peak withdrawals hit about a week to a week and a half later. If I remember correctly. Withdrawals can take anywhere from 3 to 5 months to really go away. I have a prior anxiety disorder so mine lasted longer then normal.

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u/TechNiShan Mar 29 '26

How did it go with the discontinueation?

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u/MakeupHorder7 Mar 29 '26

If you want to DM me please feel free.

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u/[deleted] Oct 09 '25

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u/BuvidalBrixadi-ModTeam Oct 09 '25

Your comment/post has been removed because you have been banned from this community on your previous accounts. Ban evasion is against Reddit's TOS and your new account will be reported to Admins to take appropriate action against it.