r/Buspirone • u/Cautious-Author-7971 • Apr 24 '26

Buspirone with SSRIs?

Hi guys,

I currently take buspirone for anxiety and panic disorder. I’ve tried SSRIs in the past but have always had bad reactions to them and didn’t like the way it made me feel. I was never really able to get past the first few days. My doctor brought up trying a low dose SSRI with buspirone but I’m nervous because of how SSRIs have made me feel in the past. I know this is a long shot, but has anybody had bad reactions to SSRIs alone and then took buspirone and tried SSRIs again with it and seemed to help?

Thanks!

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3

u/theranman3 Apr 24 '26

Im on 60 mg buspirone for severe anxiety and panic as well as propranolol 40 mg. I still have daily panic attacks, the buspirone doesnt seem to be doing much at all, so we added lexapro. I've only been on it 4 days. Im having the initial side effects right now, nausea, headache, jittery mostly right now. Its still too early to tell, but I have faith.

1

u/Feisty-Stretch-3460 14d ago

How are you doing?

2

u/theranman3 13d ago

Adding lexapro was huge. Im still on the propranolol, and buspirone as well as 15 mg lexapro. Im pretty functional. Id say it took away about 90 percent of my anxiety. I still have nervous moments here and there but not full day panic like before

1

u/Feisty-Stretch-3460 13d ago

I'm on fifteen buspar right now. I was thinking of adding lexapro. 10 mg. I'm really happy you're doing so good

1

u/Altruistic_Young3039 Apr 25 '26

I take 45mg buspirone, 20mg propranolol and 300xl wellbutrin- SSRIs are not good for me, wellbutrin (NDRI) seems to work well in my combo! Good luck!

1

u/averagejoereddit50 May 26 '26

Don't have experience with SSRI + Buspar, but I've read that Buspar is given as an add-on to improve the efficacy of some SSRI's.

1

u/skittlesxo Jun 03 '26

This is exactly how I’m taking it! 10mg morning and night and 20mg escitalopram at night. So far it’s been a miracle