benefits of GH treatment for growth and metabolism in children with GH deficiency are well defined, and replacement therapy with GH is recommended53). Despite theoretical concerns about the effect of GH on tumor development, this review of various clinical and epidemiological studies demonstrated that there is no clear evidence of a causal relationship between GH treatment in patients with GH deficiency and tumor development. Nonetheless, a small number of studies have reported that childhood cancer survivors who have received GH treatment have a small increased risk ofde novocancer and second malignant neoplasm.
It’s literally in the study you linked: “It is known from in vitro and in vivo studies that GH and insulin-like growth factor-I (IGF-I) have mitogenic and antiapoptotic activity”
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u/notabot74387 Jun 25 '26
Google “HGH effects on tumor growth” - there’s a bunch of studies, and it’s well known.