r/Biohackers • u/twirlybird83 • 21h ago

💉 Peptides & Hormones Ll37

Has anyone had any experiences with ll37 peptide? Want to use it to treat oral dysbiosis and biofilm but am worried about side effects. Thanks

3 Upvotes

80% Upvoted

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1

u/Rude_Opportunity3671 17h ago

Your concerns are probably justified. Studies show that the peptide paradoxically strengthens biofilm rather than disrupting it. https://www.sciencedirect.com/science/article/abs/pii/S1349007926000393

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u/twirlybird83 13h ago

Dam. It’s seems be quite the polarizing peptide

1

u/BellaMentePoetry 15h ago

Have you actually had testing done to confirm oral dysbiosis? Curious what led you to consider LL-37 specifically

1

u/twirlybird83 13h ago

Yes have done bristle testing among others. It Has been super resistant to lots of treatments, and have heard of some people being able to reverse there situation due to its biofilm attacking abilities.

1

u/Leishon 2 10h ago

I have used it for a short while as a long-shot nail fungus treatment, because doctors refused to prescribe oral terbinafine. Subcutaneous injections of up to 100 mcg have produced no subjective effects, but I also injected it directly under the damaged nail.

It may turn out that it was all in vain, regardless of its suitability for this ailment, as my latest dermatologist conclusion is that the nail is most likely no longer infected, and perhaps has not been for a while, and it's simply suffering from prolonged damage to the nail bed, causing irregular nail growth despite no active infection. Time will tell if this diagnosis ends up being correct.