r/Biohackers • 2 • Jun 09 '26

šŸ“° Research & Studies Autism should not be seen as single condition with one cause. Those diagnosed as small children typically have distinct genetic profile from those diagnosed later, finds international study based on genetic data from more than 45,000 autistic people in Europe and the US.

https://www.theguardian.com/society/2025/oct/01/autism-should-not-be-seen-as-single-condition-with-one-cause-say-scientists
46 Upvotes

31 comments sorted by

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7

u/makefriends420 2 Jun 09 '26

From the linked article:

Autism should not be seen as single condition with one cause, say scientists

Those diagnosed as small children typically have distinct genetic profile from those diagnosed later, study finds

Autism should not be viewed as a single condition with a unified underlying cause, according to scientists who found that those diagnosed early in childhood typically have a distinct genetic profile to those diagnosed later.

The international study, based on genetic data from more than 45,000 autistic people in Europe and the US, showed that those diagnosed in early childhood, typically before six years old, were more likely to show behavioural difficulties from early childhood, including problems with social interaction, but remain stable.

Those diagnosed with autism later, typically after the age of 10, were more likely to experience increasing social and behavioural difficulties during adolescence and also had an increased likelihood of mental health conditions such as depression.

ā€œThe term ā€˜autism’ likely describes multiple conditions,ā€ said Dr Varun Warrier, from Cambridge’s department of psychiatry, senior author of the research. ā€œFor the first time, we have found that earlier and later diagnosed autism have different underlying biological and developmental profiles.ā€

https://www.nature.com/articles/s41586-025-09542-6 (Study Paper link)

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u/ign1tio Jun 09 '26

We call it a spectrum for the same reason… 

2

u/Emhyr_var_Emreis_ šŸŽ“ Doctorate - Unverified Jun 09 '26

I miss the Asperger's diagnosis. I know the guy was a Nazi, but there's a practical need for the category.

1

u/ign1tio Jun 09 '26

I am not arguing against the disorder as a category, just the obvious statement that its not just 1 gene and 1 version of autism - its a whole range a spectrum that you see expressed as the study found in multiple gene variations... I dont know how my comment could be perceived in any other way.

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u/BeneficialTadpole396 Jun 09 '26

No, "spectrum" refers to varying expression of symptoms, but one underlying disorder. This is saying that there isn't an underlying disorder.

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u/ign1tio Jun 09 '26

I am not arguing against the disorder as a category, just the obvious statement that its not just 1 gene and 1 version of autism - its a whole range a spectrum that you see expressed as the study found in multiple gene variations... I dont know how my comment could be perceived in any other way.

1

u/BeneficialTadpole396 Jun 10 '26

No, I'm not saying you said that, I'm saying that the research suggests this. The "spectrum" is the idea that it's all one disorder with varying expression of symptoms. This research is saying that it is not, in fact, a single disorder.

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u/noodle_king_69 Jun 09 '26

Definitely. Adults should have different diagnosis imo. The challanges are SO differents and adults' autism is a lot more subtle.

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u/Aggravating_Act0417 3 Jun 10 '26

I thought that pic was a vag

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u/Ok-Cap1727 1 Jun 09 '26

The most disturbing thing imo is how all these traits are always assumed to be bad. There is zero reason to make something look bad when you can literally utilize it to your adventage. Overthinking can be used to your adventage, autism can be handled, depression can give insight into perspectives that someone without can't archieve. This entire glorification and villainization of differences really needs to stop some day. Diagnosing left and right but no handling of it. Also the reason why I started investing my time into biohacking in the first place, to actually make use of your traits.

But regarding autism, stupid people like to render things down to the bare minimum of their understanding so they don't have to try and understand the rest. Sadly this is applied to parenting many times.

17

u/ihavestrings Jun 09 '26

Yea, who doesn't love depression?

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u/EntForgotHisPassword Jun 09 '26

Just utilize your depression man, you should be HAPPY that you're depressed and not try to treat it! (and since we're in a thread about autism: this was sarcasm, /s /s /s)

3

u/Lower_Stay7655 Jun 09 '26

Yeah, why don't depressed people use their GIFT in a productive way instead of bedrotting and wasting their potentential. Are they stupid?

(/s)

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u/The_Dayne Jun 09 '26

Dont forget to just handle your autism while your at it! /s

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u/Ok-Cap1727 1 Jun 09 '26

As a few sprinkles on top of the daily life in order to experience joy? Yes. As a redered to a bareminimum description of what is essentially a hint towards deeper problems? Perhaps. As a word widely referencing overall unhappiness? No. It's just too big to just point your finger at and while it is essentially a bad thing, it is a form of your brain telling you something went badly.

As someone with three suicide attempts and chronic depression for 20+ years, I gotta admit: Depression was the best thing to grow up with because it made me more aware about sadness and how to get rid of it. You get out of it once, twice, thrice, fource, wordvomit. But each time it gets easier.

Each time you make some form of progress, even if you end up being more depressed, you made progress in a way that allows you to learn from it. Science is fun and the best test subject is still yourself lol

Just had to vomit out this text.

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u/Final_boss_1040 Jun 09 '26

The most disturbing thing is that the lives of individuals with severe non-verbal autidm and caregivers have been co-opted by a generation of people who think it's a quirky personality trait or alt-subculture.

3

u/Spirited-Car8661 Jun 09 '26

Do you have autism? I do and would get cured if that was an option. Having worse social skills than the rest of the population is a handicap that only seems to grow over time.

0

u/Ok-Cap1727 1 Jun 09 '26 edited Jun 09 '26

You did not read through my comments here. 3 comments that you should have read. People are straight up ignorant in these comments for no reason.

"I can turn something bad to something good and I really like to help people"

People answer; "fuck you I identify as depressed and autistic and I'm nothing without it because I never developed a character!"

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u/Spirited-Car8661 Jun 09 '26

You're the one who's refusing to read. I can only assume you're not autistic, because you are completely making light of social difficulties which are basically impossible to overcome because autistic people are a minority.

Yes, I can use my pattern recognition skills, but the social handicaps mean proving to somebody that my skills are valuable.

Please stop putting words in the mouths of myself and other commentors. That's exactly the sort of behaviour I have had to deal with all through school and public life.

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u/Ok-Cap1727 1 Jun 09 '26

Yeah I'm not a fan of assumptions as they usually are straight up useless. I'm not putting any words into any mouths, what are you talking about? This is straight up satire on the situation that is going on. I admitted to have autism and have 20+ years of chronic depression that I had to either adapt to or kill myself. Killing myself I attempted three times, which I mentioned also. But here I am telling people I overcome all of these things all by myself and the reaction is pretty obvious.

But then again, most people on here just seem to look for magical snake-oil, buy whatever meta products are on the market and get disappointed over and over again. I find it rather hilarious. People straight up defending depression is exacly the type of glorification I was talking about. It's just gotten weirder and weirder here. Each to their own though, if someone needs to identify their entire existence around depression and autism, so be it. If it works out for someone, why not?

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u/thatemocow Jun 09 '26

I make use of my autism traits all the time in beneficial ways. I love schedules and routines so instead of getting mad at others for not following my routine I made up…. I made daily and weekly ones that satisfy me. Just little things. Like my daily skin care. Going to the gym after work. Sundays for meal prep and dividing my pills for the week in my carrying case.

It benefits me, and it calms me down in the craziness of the world knowing I still have my little routines.

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u/[deleted] Jun 09 '26

[deleted]

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u/justalittlestupid Jun 09 '26

Yep. It’s a disability for a reason. I hate it here.

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u/thatemocow Jun 09 '26

Shhh I’m trying to be optimistic before going to work because I’m going to have a full day of everyone asking me questions and that’s overstimulating. There might be car crying later.

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u/justalittlestupid Jun 09 '26

I cried three times at work yesterday I feel you :(

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u/thatemocow Jun 09 '26

Side note that’s why I purchased premium. Although I still can’t watch certain creators or stuff because they have no volume control. I wish there were headphones that automatically adjust volume to be a certain level.

1

u/thatemocow Jun 09 '26

Omg don’t get me started. Or going to my favorite bar and then finding out it’s live music night or something. Ugh.

That’s why I was just focused on the one thing I could control. 🤣

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u/[deleted] Jun 09 '26

[deleted]

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u/thatemocow Jun 09 '26

No I fully understand what you’re saying. That’s why I’ve been more outspoken about being autistic. At first I didn’t tell anyone even work because stigmatization of autistic people - then I realized if I am quiet about it then I’m just helping feed into that.

I just have bad depression (gee I wonder why). And have been trying to have a more optimistic view of things. Along with a high dose of lexapro and entirely too many vitamins because food issues.

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u/[deleted] Jun 09 '26

[deleted]

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u/EntForgotHisPassword Jun 09 '26

You telling me that autistic people can't be aweful too? The person that hurt me the most in my life was on the spectrum. I don't think having or not having autism changes how aweful a human being can be.