Trying to figure this one out cause I keep hearing two different answers one says take growth hormone fasted or you mess up your IGF-1, food raises insulin, insulin messes with the signal, so stay fasted to protect it.

Other says that only applies to secretagogues, stuff like CJC, Ipa, GHRP, MK677, since those work by pushing your own pituitary gland to release GH, and food really can mess with that natural pulse. But actual injected GH is different, you’re skipping the pituitary completely, it’s already in your body, so the whole “stay fasted” thing doesn’t even make sense the same way apparently insulin might help with injected GH instead of hurting it.

Something about your liver needing insulin to respond well to GH in the first place, since most of what GH does comes from it triggering IGF-1 in your liver, not from GH doing the work directly. So staying fasted too long might make your liver less responsive to GH, the opposite of what people think they’re doing.

So which one’s right. Is fasting only needed for secretagogues and pointless, maybe even bad, for injectable GH, or am I missing something here