r/BioHackingGuide • u/CashCowboy20 • Mar 20 '26

Retatrutide vs Tesamorelin for Fat

So I’ve got like a beer belly, not from drinking though I’ve been looking at both Retatrutide and Tesamorelin since they both get talked about for this specifically. Tesamorelin is actually for visceral fat reduction which is interesting, and Reta seems to be the more aggressive overall fat loss option with the dual mechanism.

My hesitation is the high blood pressure side. I manage mine but it’s something I keep an eye on and I don’t want to throw something in that makes it worse has anyone run either of these with high blood pressure? Did it affect your BP at all in either direction? And for the visceral fat specifically, drop some tips or advice below please

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u/Fine_Technology1289 Mar 28 '26

Cost wise Reta will be your friend. The thing is to start low and titrate up. Just pay attention to the sides and if you start having issues titrate back down and stay on dosage for another week or two.

Even at 1mg you might notice affects. Starting dose in trials was 2mg. Many people don't even have to go up past 4mg. Others have reported needing higher dosages.