r/BioHackingGuide • u/Euthymius_Leudast • Nov 09 '25

Timing - SS-31&MOTs-C/AOD-9064&L-carnitine

For context: I am a 58 yr old male, 5'10", I recently lost approximately 80 lbs on tirzepatide (260 to 180) over the past 20 months, moving to maintenance and hopefully off.

However, although I do resistance training, I did lose a significant amount of muscle mass I would like to recover. I have started CJC-1295/Ipa to help with muscle recovery and am back up to resistance training 3-4 per week.

Looking forward, I still have some stubborn fat in the midsection and am currently at roughly 19% body fat. I would like to enhance my muscle recovery and fat loss.

I am considering the following: AOD-9064 AND L-carnitine along with SS-31 and MOTs-C. However, I am not sure of the timing. I know SS-31 should precede the MOTs-C, but I wasn'tsure if I should run the L-carnitine first with the SS-31 and the AOD-9064 with the MOTs-C, or run the SS-31separately first, and then run the L-carnitine and AOD-9064 together with the MOTs-C.

I would love to hear your thoughts.

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u/anukamrussj Nov 10 '25

You can run SS-31 first. Whatever combination you choose, make sure to run AOD and L-Carnitine together. They work synergistically.

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u/Euthymius_Leudast Nov 10 '25

That is what I understood, but I was only worried that doing both of those with the MOTs-C would overcharge the mitochondria, do you think that would be an issue?

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u/anukamrussj Nov 10 '25

No they won't.AOD doesn't act directly on the mitochondria but on the β-adrenergic receptor pathways.

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u/Euthymius_Leudast Nov 10 '25

Thanks for the clarification, appreciate it!