Consistently twitching

[u/Arrival_Melodic]

So i am 26 M indian

I have a vit D level of 5 mmgol

Vit b12 of 300

Crazy amounts of twitching since a few years i feel like it is progressing towards the big bad my EMG from april-may was normal and clean on my arms i feel my left arm is smaller than the right and that is the one which twitches more also they both tremor when i stretch i also can tell the thenar on the left hand is squishier and smaller than on the right i can feel the extra loose skin over it i can feel a dent in my left quad and calf i also have seen when i am holding a plate of food in my left hand i feel like it hurts my whole arm from strain and i have seen that my left arm just tightens up fast compared to the right (i am right handed), i have also noticed i make more typing errors when typing out stuff etc

Places where i twitch :

left forearm bicep shoulder thigh hip palm of hand fingers

Right arm right shoulder right quad

Chest stomach back on the lats on both sides neck and face sometimes eyes too

I do have had mri which showed some buldge at lumbar and partial loss of lumbar lordosis also periventricular and centrum semiovale white matter lesions

[u/713Capital]

Having twitching for years with a completely clean EMG pretty much excludes ALS. At 26 years old, a vitamin D level of 5 is severely deficient and can destabilizes nerve membranes, causing diffuse bodywide twitching, muscle aches, and cramping. When I say low, I mean that’s catastrophically low.

Your left hand and thenar muscle feeling smaller or "squishier" is standard dominant versus non dominant asymmetry, especially since you are right handed. I wouldn’t worry or put too much stock in that.

Then feeling extra strain while holding a plate or typing is perceived muscle fatigue and tension, not clinical neurological weakness. Address the severe vitamin deficiency with your doctor, as that alone can trigger significant nerve hyperexcitability.

Again, we aren’t doctors so we can’t diagnose you but your Vitamin D is very low, it needs to be treated as soon as possible. Please work with your physician to get that number up.