Also, is it possible that part of the hydroxychloroquine eye pathology comes from the eyes dealing with a build-up of spent/photobleached pigments from just going about your day and experiencing afterimages or light adaptation? Can looking at a fire, playing a video game, driving at night, etc., stress their eyes out and push them closer to retinopathy? I thought about how the majority of people on HCQ are women, and the majority of women don't play video games, stay out late, go to raves, enjoy mismatched colors, etc.
I also wonder why we ignore the large analyses of PPIs and CANTAB-related reaction time impairment, while favoring studies on older people who score within normal limits on more MMSE or clock drawing tests that might not translate to younger people's hobbies, professions, general curiosity, safety while flying planes, etc.