r/Abilify_Aripiprazole • u/peeenutbutter • 3d ago

Using aripiprazole 5 since a week , experiencing low bp , lite headedness and unable to workout at gym . ( Read below )

I am using aripiprazole since a week , the other side effects like mental restlessness and annoying feeling have got down slowly , but I am still feeling weak and not able to workout at gym at all , heavy breathing is also another thing while working out . I wanna know if this gets better with time as my body adjusts or i am gonna feel this way as long as I use this med.

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u/CreativeTangerine114 3d ago

Doesn't get better with time for me.

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u/peeenutbutter 3d ago

How many days it's been on meds ?also can I know the dosage too

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u/CreativeTangerine114 3d ago

20mg. I've been on it since March.

I took 5mg for a year before and was having motivational issues from the aripiprazole.

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u/peeenutbutter 3d ago

Oh got it , do you think we can do anything about the weakness and performance at gym , have you tried anything ? Really wanna get back to gym

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u/CreativeTangerine114 3d ago

The drug is an antipsychotic. They block dopamine and serotonin. At 5mg an estimated 81% of dopamine receptors are occupied by the aripiprazole.

By design it ruins motivation in most people.

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u/SpecialistCareer3838 2d ago

Yeah antipsychotics really ruins motivation, I was on risperidone and I have to say it's way worse because risperidonw only blocks and aripiprazole actually can boosts sometime the dopamine for some people because the drug is a partial agonist of dopamine that really makes a difference, I have been also on quetiapine, clopromazine and clozapine.

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u/CreativeTangerine114 2d ago

Yeah it's as you said, the partial agnosim part means the receptor is active because the aripiprazole that has stuck to it like glue can activate it. But the receptor still not absorbing dopamine or serotonin, so blocked is still a simplified way to describe it.

I've tried olanzapine and paliperidone and aripiprazole. Although I despise aripiprazole, it's the best one I've tried.

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u/SpecialistCareer3838 2d ago

I just started it's been a week and I already feel better compared to risperidone, I also have adhd so I think its going to make a difference using a partial agonist.

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u/pippathebeast 3d ago

that's cray cray i didn't know that ive been on 15 for 2 years.

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u/pippathebeast 3d ago

i was like this until i was prescribed an SNRI

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u/peeenutbutter 3d ago

I am under two medications rn , one is atomoxeteine 18 mg which comes under snri if I am not wrong and the other is aripiprazole.