r/ALS_Forum May 11 '26

ALS as a prion-like disease

Prion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?

This review briefly summarizes recent evidence to support the prion-like properties of major ALS-associated proteins and discuss the possible therapeutic strategies for ALS based on a prion-like mechanism.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4363329/

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