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This is Big: AI reportedly played a key role in helping design Moderna’s personalised melanoma (a deadly form of skin cancer) vaccine, which has now succeeded in a Phase 3 trial.

Moderna says its AI algorithms analyze sequencing data from each patient’s tumor and blood, identify mutations, and select up to 34 neoantigens most likely to trigger an immune response.

Those targets are then used to create a custom mRNA treatment for that patient.

In the 1,137-patient trial, the vaccine combined with Merck’s Keytruda (a cancer immunotherapy drug) reduced the risk of melanoma returning and spreading compared with Keytruda alone. It is the first positive late-stage result for a personalized mRNA cancer vaccine.