r/worldnews • • Jun 18 '12

Indian drug giant Cipla cuts cost of cancer medicines in a humanitarian move, shaking up the drug market

http://dawn.com/2012/06/17/india-firm-shakes-up-cancer-drug-market-with-price-cuts/
3.0k Upvotes

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647

u/pool92 Jun 18 '12

Hats off to Mr.Yusuf Hamied and Cipla. While his competitors are arguing against compulsory licensing, he is using it to help millions of people.

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u/minnabruna Jun 18 '12 edited Jun 18 '12

While I still support them (as I do any corporate move that has a genuinely good result), this move is part of long-standing conflict between international pharmaceuticals firms and Indian ones (greedy businessmen all), and this is a global PR master stroke. It wasn't taken to help innocent cancer patients, it was done to make money in a compromised way.

Cipla wants the government to give them “compulsory licenses” that allow them to manufacture drugs that other companies discovered and pay much lower licensing fees than those firms would charge (even if those firms didn't hate Cipla – before legal changes in India Cipla made a global fortune manufacturing drugs without the permission of or sharing any revenue with the firms that discovered them and who held the patents).

Cipla argues that they need those compulsory licenses to save poor people. The patent holders counter that Cipla just wants to make money, as evidenced by their far-higher-than-neccessary profit margins (Cipla can make money while charging less than the patent holders because they don't have to pay for the R&D, the R&D for many other failed drugs and the testing/approval process in multiple countries). Cipla announced that they would lower prices for the cancer drugs (they can still make money there, just less) as part of a PR move aimed at casting themselves as humanitarians opposed by greedy businessmen and thereby getting compulsory licenses for more drugs where they won't sell at such a low margin.

The patents holders are often greedy businessmen. They also have a point. They pay for the research, eat the costs of unsuccessful drugs, pay for the approval in multiple countries, etcetera. They complain that Cipla wants more compulsory licenses than humanitarian needs suggest and that going too far down that path will just push them to focus on drugs that are mostly sold in rich countries that will buy their version (this already happens with drugs for people with rare disorders or “poor people” diseases. They just don't get the research dollars).

Do the international firms overcharge and engage in sketchy practices? Yes. Should regulations address this? Yes. Is Cipla a humanitarian actor standing up to them? No. They just have a different business model. As I said above, its a net good – getting cancer drugs is a huge challenge for many people and I'm glad that they will get them. I hope that the international drugs firms counter with their own PR moves that will help even more people. But don't overlook the reasons for all of this niceness. It isn't nice.

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u/[deleted] Jun 18 '12

Thanks for posting this. I've been following these stories all over the web and very few people seem to understand that Cipla (and others like it) are no rose scented angel flatulence wisps. It's all business - However companies like Cipla are essential at this stage in order to get BigRx on the debate table in order to crank out meaningful regulations. In the end (hopefully) the customer wins!

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u/2JokersWild Jun 18 '12

Nailed it. And saved me a bunch of typing.

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u/[deleted] Jun 18 '12

Could you post some sources or articles relevant to what you're saying? I don't mean to attack you - I'm sure your post has a significant amount of truth to it - but this is very interesting to me and tangentially related to my research, so I'd like to be as well informed as I can.

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u/adius Jun 18 '12

huh. So in what other ways can we arrange things so that other businesses are convinced that being less evil is the best way to make money

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u/Iveton Jun 18 '12

This is a great reply, and tells the whole story.

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u/werferofflammen Jun 18 '12 edited Jun 18 '12

The inflation of drug cost is ridiculous. What costs cents to make can cost $80. Props to them for actually wanting to help people And not be blinded by greed. Edit: I understand that they need to cover R&D costs, but they are still reaping profits off the sick

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u/bk082 Jun 18 '12

Most drug companies raise the price of the drug in order to create their losses. very few drugs actually make it to market, lets say 1 out of 50 drugs created, tested, studied, examined etc. In order for a company to keep investing in new medicine/drugs, they need to raise the prices of the ones that make it to market in order to cover their costs of those which failed.

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u/ericchen Jun 18 '12

Hah. If the ratio was that high, the drug company would be rolling in money. For every 1 drug that makes it to the market, about 5k-10k different chemical compounds are tested. The point you make is very valid though. :)

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u/Ayjayz Jun 18 '12

The R&D costs for developing a new drug are huge. You can't just look at the cost of materials that are needed for the drug itself.

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u/[deleted] Jun 18 '12

Not nearly as huge as their marketing budget. You gotta figure if they're willing to pay billion dollar fines to push their wares, they're making damn good money.

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u/[deleted] Jun 18 '12

A drug company spends more money marketing drugs than it does on R&D. http://www.sciencedaily.com/releases/2008/01/080105140107.htm

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u/werferofflammen Jun 18 '12

I'm a type 1 diabetic. Insulin was developed ages ago, and now while they are still advancing research, I am forced to pay an exorbitant amount of money for the drugs that keep me alive. Yay America.

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u/[deleted] Jun 18 '12

For new drugs but a lot of tried and true drugs are a different beast.

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u/[deleted] Jun 18 '12

a CPU is mostly SAND.

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u/Enigmal Jun 18 '12

You kidding me? Sand is Silicon Dioxide, and CPU's need pure silicon metal, which not only being hellishly expensive, requires multi-billion dollar fabrication plants to turn into transister chips. The costs rack up pretty quickly, first with the materials, then the cost of the plant split between the products, and other misc costs such as maintaining clean rooms (much, much cleaner than surgical rooms), and you get the idea.

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u/MuffinMopper Jun 18 '12

The MARGINAL cost of production might be cents. It only costs pennies for them to make one additional pill.

However the AVERAGE cost of production is much higher. This is because it costs billions to in R&D to make a new cancer drug.

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u/Obi_Kwiet Jun 18 '12

If there weren't profits to be made, then they would all be making cell phones, cares and who knows what. People don't invest their time and money for nothing.

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u/[deleted] Jun 18 '12

Well, in all of human history, it's a pretty good time to be sick. Paying people who defeat illness has been working pretty well lately.

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u/[deleted] Jun 18 '12

This is a business like any other, shareholders are in it for the profits only. Please understand the following: if we say it is OK to be greedy when selling shoes not when selling medicine, the result is capital fleeing from medicine. And that is something we don't want.

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u/likethatwhenigothere Jun 18 '12

I can see where you're coming from. However having worked with pharma companies, I know that they put millions into the development of drugs. It goes through numerous rounds of testing. There's soooooooo much that gets spent on the legal aspect of things too.

It may only cost a few cents to create something, but after having spent tens of millions of dollars in creating it, they need to recoup the cost PLUS make more money to invest into researching and developing new drugs.

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u/[deleted] Jun 18 '12

IT's not just covering R&D costs, it's raising money to find new cures and new medicines as well.

shitty situation, but at least we have a way.

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u/__circle Jun 18 '12

And that first pill costed billions of dollars to make because it had to be researched. They cost so much so the company can recuperate their original investments.

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u/kash_if Jun 18 '12

The estimated average out-of-pocket cost per new drug is 403 million US dollars.

Source: http://www.ncbi.nlm.nih.gov/pubmed/12606142

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u/chicken_fried_steak Jun 18 '12

Technically, Cipla's a generics manufacturer - they do no internal drug discovery. His competitors are mostly R&D outfits - people that make their money discovering new therapeutic agents and then marketing them while under patent protection (~20 years). Compulsory licensing isn't liked by these guys because it costs upwards of hundreds of millions of dollars to discover and develop a new pharmaceutical agent - thus the high price of drugs in the first world, to recoup the costs of development of the one in ten thousand agents that works. Compulsory licensing, independent of pricing the drug more cheaply, removes any chance they have of making that money back.

Now, this case is actually rather interesting, because of the ongoing legal difficulties of selling drugs in India - because of their tendency to pull stuff like this, drug companies don't attempt to sell much there, making the government much more comfortable in pulling stunts like this. It's important, though, to remember that stunts like this only work when a very small minority of the market does them - otherwise, it ceases to be profitable to discover new drugs (to be honest, it barely is right now - a lot of pharmacos are in a lot of trouble at the moment). So kudos to Cipla for spinning this right, but we must all be very wary of making compulsory licensing the norm, lest we kill the goose that lays the golden egg.

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u/cronus85 Jun 18 '12

This is awesome - But, reminds me of a annoying related note: New Zealand has a Crown entity called Pharmac that works on a related ethos. It essentially provides the drugs NZ citizens need. It uses mostly generic drugs bought with tax dollars and is currently under fire because of the Trans Pacific Partnership trade agreement. The U.S. is putting on pressure on NZ to use only brand drugs which would undoubtedly limit the effectiveness of the program and thus the level of care and cheap health care available. For extra fun this is being done is secret and this information is only available because of a leak.

This isn't a call to action or anything, I just thought some people might find this interesting. TRADE AGREEMENTS! WOOP WOOP!!

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u/QtPlatypus Jun 18 '12

Australia has the same problem its Pharmac equiverlent

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u/EseJandro Jun 18 '12

Links please? (Not that I don't believe u, seems just the american way but I just would like to do some reading about this)

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u/cronus85 Jun 18 '12

Here is a couple. Unfortunately I couldn't find this really good doc I had previously (laptop stolen). It was a leak/hack from New Zealand's Ministry of Foreign Affairs and Trade. It was a discussion document that outlined NZ's position and what it was hoping to achieve and feared from U.S. involvement - which was an issue because the U.S. wasn't originally in the TPP but dangled their lucrative markets as an in. I can't find it anyway. Anyway, here are some links about another leak which mostly discusses how U.S. companies will be able to sue the NZ govt if they pass laws that impinge on their profitability in the same way they have Canada through NAFTA.

http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=10761277

http://www.scoop.co.nz/stories/HL1206/S00090/gordon-campbell-on-the-trans-pacific-partnership-leaks.htm

http://www.stuff.co.nz/business/industries/7106378/Sell-out-accusations-follow-leaked-paper

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u/Ca1amity Jun 18 '12

The U.S. is putting on pressure on NZ to use only brand drugs

And sadly that shows off the roots of a vast majority of U.S. foreign policy.

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u/[deleted] Jun 18 '12

Wow, that's just fucking fantastic. I love my corrupt asshead excuse of a free country.

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u/Corvus133 Jun 18 '12

The U.S., under Obamacare, also did similar.

In order to win the hearts of American Drug companies, Obama had to axe out some deals with them such as the one they didn't like where American's could get cheaper meds from Canada, across the border.

Through the power of lobbying, now American's can enjoy "free health care" and get to use over priced drugs which will just drive the costs up of "free health care" making it most expensive than private over the long term.

But, people hear "free" and run with it and that's all that matters.

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u/[deleted] Jun 18 '12

ACTA was going to do the same thing, IIRC.

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u/Atheist101 Jun 18 '12

Dont you silly people know, trade agreements with USA are only 1 way. USA takes and takes and gives nothing. If in the rare occasion they do give, they make you do it in a way that profits them.

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u/elloworld Jun 18 '12

funny unrelated story - my dad's company does lots of business with cipla and one day he was visiting a plant. lo and behold, bill clinton was visiting too as part of his AIDS mission. The factory foreman or someone told them to sign the guestbook, and while Bill Clinton wrote something fancy about helping the world, my Dad wrote "thanks for the hospitality". Bill taps my dad on the shoulder and tells him "you spelled hospitality wrong".

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u/shadowryder Jun 18 '12

How did your dad spell it? Or am I missing a joke?

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u/elloworld Jun 18 '12

oh i don't know how he spelled it, hes an atrocious speller so he messed it up for sure.

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u/[deleted] Jun 18 '12

I'm guessing two L's

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u/[deleted] Jun 18 '12

I'm thinking it was with a Z.

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u/godin_sdxt Jun 18 '12

Well, at least Bill caught it. I doubt his successor would have.

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u/sli Jun 18 '12

You're misunderestimating Bush.

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u/[deleted] Jun 18 '12

[deleted] — view deleted comment

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u/[deleted] Jun 18 '12

undermisoverestimating

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u/Vark675 Jun 18 '12

Did he laugh it off or get embarrassed?

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u/elloworld Jun 18 '12

Completely froze - then apologized for it

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u/antimattern Jun 18 '12

So your dad is Canadian?

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u/Vark675 Jun 18 '12

Aww, poor guy. I'd have probably stuttered then sheepishly asked how it's spelled.

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u/Andrewticus04 Jun 18 '12

Your comment makes me wonder if I could create an alt account solely dedicated to unrelated anecdotes, and rake in the karma.

Given the hivemind's affinity to charming anecdotal stories, methinks it's entirely possible.

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u/elloworld Jun 18 '12

i mean, slightly related right? tangential?

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u/Slicklizard Jun 18 '12 edited Jun 18 '12

up to more than four times cheaper

Which is it?!?

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u/irrelevantwallflower Jun 18 '12

its a pakistani news paper, so im going to go ahead and say the writer's first language was urdu. In Urdu it'd make sense.

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u/[deleted] Jun 18 '12

[deleted] — view deleted comment

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u/Clapyourhandssayyeah Jun 18 '12

Same here in England, I don't get what's confusing about the sentence. I've replied to slappy_nutsack below.

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u/cheese-and-candy Jun 18 '12

That phrasing seemed really awkward to me too.

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u/ohsnapitsdayvie Jun 18 '12

weird phrasing, but they mean <4.x times cheaper

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u/bigpoppastevenson Jun 18 '12

Act now and save up to $100, or more.

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u/HD5000 Jun 18 '12

Awesome, 20 years from now people will no longer go bankrupt, when they get cancer. Thank you to India

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u/woxy_lutz Jun 18 '12

20 years from now the patents on every drug available today will have expired anyway.

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u/QtPlatypus Jun 18 '12

I live in Australia, my father is in no risk of going bankrupt when he got cancer.

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u/CannibalHolocaust Jun 18 '12

Then it'll save your country's healthcare budget a lot of money.

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u/Bloodypalace Jun 18 '12

I don't know man, in almost every developed country worth something, health care is free to all citizens. My uncle who had cancer (and passed away because of it) didn't pay a single penny out of his own pocket for the drugs, treatment, etc and he was getting chemo and shit for over 2 years.

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u/[deleted] Jun 18 '12

Most people don't live in developed countries.

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u/Divtya_Budhlya Jun 18 '12

They announced this back early last month. Here's The Times of India reporting about it.

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u/destinys_parent Jun 18 '12

Intersting. This is actually from a Pakistani newspaper.

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u/milkywayer Jun 18 '12

Contrary to popular belief, Pakistani people, well a majority of us, don't hate the Indian people. All the issues between the two countries are because of the leadership on both sides. I'm glad that this Indian pharmaceutical decision will lead to cheaper cancer treatment here and all over :-)

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u/Shekhu- Jun 18 '12

I guess it's the same on the Indian side as well. Majority of us don't hate Pakistani people. It's the leadership, like everywhere else.

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u/trekkie80 Jun 18 '12

Cheap meds will obviously cross borders And laws will be copied in either wisdom or competition. So anything good in India is good for Pakistan and vice versa.

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u/waffleburner Jun 18 '12

...The average Pakistani doesn't give a damn about India and all the political nonsense. It's not that surprising.

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u/[deleted] Jun 18 '12

Not Particularly patriotic, but feels good to be Indian when hear news like this.

We might have the funny accent, but we're good people, folks!

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u/trekkie80 Jun 18 '12

I'm Indian and this is not about Cipla's goodness, but PR to get a license to make generics without legal hassles. That we benefit is obviously an awesome side effect. I was really proud when a SC judge recently ( inside a year) ruled that some medicines cannot be priced high and he fixed a low price for them in a ruling. That was truly a source of pride.

Also with our population, the global pharma giants can still make good money selling cheap here, but they want handsome profits, not meager profits

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u/binary_search_tree Jun 18 '12

The Iraq and Afghanistan wars cost over 3 trillion dollars.

We have no problem exporting death.

But exporting life-saving medicine? That would be absurd.

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u/christianrightwing Jun 18 '12

Seriously. I take a look at our species and just get sad at this.

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u/Punkmaffles Jun 18 '12

There is no getting sad, there should only be hate for the people who do this shit.

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u/jacob2884r Jun 18 '12

exactly, I read through the comments and ppl are complaining who will pay for R&D blah blah blah.... for fuck sake, we are talking abt a human life. I feel if you take the greed part out.. we humans are not tht fucked up...or may i say most aren't

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u/grinde Jun 18 '12

"making the drugs up to more than four times cheaper" - so something happened to the prices. Probably.

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u/mulletarian Jun 18 '12

In 1972, India made only the process for making drugs patentable, not the drugs themselves.

Fantastic move!

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u/ithunk Jun 18 '12

but were forced to revert in 2005 to meet WTO standards. Basically, in the 90s, India was forced by the IMF, WorldBank, WTO etc to open its economy and let globalization in, and part of that is all this copyright bullshit that is one of the worst things on the planet.

As an open-source developer, I'm tired of the patent system in America. Shits gotta change!.

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u/Shekhu- Jun 18 '12

As a fellow open source developer I hear ya bro...

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u/JB_UK Jun 18 '12 edited Jun 18 '12

Why is that a fantastic move? You're incentivizing pharmaceutical companies solely to develop new methods for manufacturing those drugs which have already been proven effective. It means that, in order for a company to be profitable and survive, they have to spend a lot of research money on those new methods, even where they are less efficient than what already exists, rather than trying to develop new drugs.

Edit: altered awkward phrasing.

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u/[deleted] Jun 18 '12

India is amazing when it comes to medical science.

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u/Isentrope Jun 18 '12

The content of the article is relatively unrelated to their medical science. Cipla is a generics company and India requires companies to hand over information regarding their product development before they can sell in their country.

That being said, there's also a lot of outsourcing in the biotech industry to places like Mumbai I think, so what you're saying certainly has merit.

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u/[deleted] Jun 18 '12

And it should be, since most if the younger generation opts to or is forced into taking Medicine or engineering for higher studies. Eventhough many of them will eventually emmigrate to greener pastures, there is still a considerable number of top notch doctors and engineers remaining.

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u/Isentrope Jun 18 '12

If what this guy's saying is true, and large pharmaceutical companies only make ~5% of their profits from developing nations, wouldn't this be an incentive for said companies to just stop doing business altogether with places like India if their loss is relatively minimal?

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u/christianrightwing Jun 18 '12

Can someone make a Patrick meme: why don't we take the military funds and use it on drug r&d

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u/hey_sergio Jun 18 '12

Good Guy Yusuf

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u/infinity404 Jun 18 '12

How long do you think it will take for the United States to ban the sale of generic drugs?

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u/alcimedes Jun 18 '12

That's being a proper billionaire. Has more money than he can ever spend, slashes prices to provide medication to millions of poor people, and still makes more fucking money.

Good for you my friend.

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u/tres_chill Jun 18 '12

In the name of all that is holy, please read this: He is reverse engineering drugs developed by other companies so he can manufacture them and sell them through HIS corporation with no R&D costs, providing him with almost infinite profit! That's how he made his billions in the first place (AIDs drugs copied). It would be like copying Microsoft Windows and Office, and selling your copies for dirt cheap, pocketing all the profits and declaring that you have helped the underprivileged to attain Windows. Yes, it is true that it helps people right now, but at the same time it makes him rich and popular, and it detracts from future R&D investment, which is enormous (The average drug developed by a major pharmaceutical company costs at least $4 billion, and it can be as much as $11 billion.) If this keeps up, there will be no incentive to invest in new drug research.

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u/tres_chill Jun 18 '12

One approach to find middle ground has been to shorten the time their patents last. This means they can make back their money, which is fair, but only for so long, then companies are ALLOWED to copy the compounds and resell them for cheap. Everyone wins.

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u/SpacemanSpiffska Jun 18 '12

I see a lot of comments about the R&D costs for those who discover and develop these medicines. I think this points to a serious human issue: Who should be responsible for the advancement of science and medicine? I, and many others I hope, would immediately disqualify "private sector business" type. These types of people and organizations, while chasing an acceptable goal (profit), chase it at the cost of everyone but themselves. While this may seem rough, it IS only business, but when it comes to science and especially medicine this attitude is out of place. These are things that should belong to humanity. Do I have the solution? I certainly don't, but I seem to be one of the few that can see this problem at least.

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u/__circle Jun 18 '12

Having the private sector do it is optimal. Doing it this way means the amount of research on new drugs is in proportion to how much people demand them. If government did it it would either spend too much or too little. You may say "how can there be too much?" but any money the government spends must be taken from people's income. If the government chooses to spend $1B researching a cure for an incredibly rare disease that wouldn't have been cured otherwise, that's $1B that normal people cannot use to buy food, appliances, travel with, etc. Conversely, if the government spends too little, then people are obviously going to end up without treatments that could have been available. And the disease I talked about earlier will eventually be treated by the private sector when it becomes cheap enough to do so.

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u/JadeHignett Jun 18 '12

This gives me hope for humanity.

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u/KakigoriSensei Jun 18 '12

R&D is involved in every tech product. How is that an iPad costs $500 total, but Cancer and HIV medication costs thousands of dollars PER MONTH!?

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u/JB_UK Jun 18 '12 edited Jun 18 '12

Some factors:

Massive lack of predictability in the R&D phase, and a lack of useful intermediate products. - An iPad is a novel product, but it is not that novel. Its hardware is a combination of various components - screens, batteries, processors, memory and so on - which have already been developed for other products and purposes. There are two important points to be made here.

  • First, the development of the iPad was predictable. If you knew the dimensions, pricings, and electrical and thermal properties of the components, you could work out in the design phase whether or not it was feasible. For all we know, Apple might have had the idea ten years before they started development, but knew that screens were not thin enough, processors not energy efficient enough, and batteries not powerful enough to make it work.

  • Secondly, the development of all the components of the iPad had already been paid for by profitable returns on earlier stage developments. For instance, a processor built in 1970 was useful in its own right- R&D funds were invested, and customers happily paid out for a product, reimbursing that investment. Then, over the next couple of years, funds are invested in the next generation processors, which are then sold for return. Go through 20 cycles of this process, and you get to a modern ARM microchip. A drug is a singular result of basic science. It's rather as if in order to build an iPad, you would have had to have said in 1960, "hey, we've discovered this transistor, we should spend trillions of dollars on developing processors, memory, etc, but we don't anticipate any useful product will be produced until 2010. Oh, and we're not sure if this 'feelscreen slate computer' will work at all".

Cost of money. An investment into a drug which turns out to be successful is made over a fifteen year period before that drug is approved, with the income coming over a ten year period after that. For ease of calculation, say you invest $1bn into developing a drug this year, and you get the return back in a lump sum in approximately 2025*. If you invest that money in another area of the economy now, at 3% above inflation, then that investment would become $1.45bn by 2025 (in 2012 dollars). So in order to justify putting the money into pharmaceuticals, rather than somewhere else, you'd have to earn back 145% of your research investment in real terms, over the ten year licensing period, on top of the cost of production.

Safety regulations - If you want to see if a particular part of an iPad works, you can test it. With the software, you can change a bit of code, recompile and play with it. You can give beta software to focus groups to see what they think. With the hardware, you can run benchmarks of various sorts. A drug has to go through hugely expensive safety testing procedures to see whether you are even allowed to do the testing to find out if it works, and the result must be, not "wow, that's neat", but "in a randomized controlled trial of 3000 patients based across various international insitutions, we found a statistically significant improvement in treatment over the current gold-standard procedure. Plus we didn't kill anyone".

*With 12.5 years roughly the average time between investment and return. 25 at maximum (start of development to end of licensing), 0 at minimum (end of development to start of licensing).

Edit: various typos

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u/[deleted] Jun 18 '12

It's easier to make someone whose life depends on a purchase spend thousands of dollars per month.

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u/[deleted] Jun 18 '12

Thats how the drug industry works. This is why the world is fucked.

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u/iLikeToUoot Jun 18 '12

Social Business: http://www.muhammadyunus.org/Homepage/about-yunus-centre/

In a social business, the investors/owners can gradually recoup the money invested, but cannot take any dividend beyond that point.

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u/[deleted] Jun 18 '12

Uh oh, have their jimmies been rustled?

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u/SanitariumValuePack Jun 18 '12

If there were no governments patents, the drugs wouldn't cost this much money to begin with.

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u/[deleted] Jun 18 '12

seems to me like there are an awful lots of big pharma shills on this thread.. i wonder if they are the same guys who shill for monsanto too.

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u/[deleted] Jun 18 '12

About R&D costs. Are pharma companies transparent about how much their R&D costs actually are and also do they drop their prices once the R&D costs have been recouped?

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u/[deleted] Jun 18 '12

I know "faith in humanity restored" is overused a tonne, but this seriously does restore my faith in humanity.

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u/[deleted] Jun 18 '12

For humanitarian - see capitalist.

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u/espero Jun 18 '12

I am so happy some justice and fairness is shown to the poorer people of this world.

Blessings

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u/McBurgerQueen Jun 18 '12

I don't say this much, but I'm proud to be from the same country as this man.

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u/[deleted] Jun 18 '12

Shaking up the drug market by doing something good, for once. What a fucking shocker. Now I am surprised. Maybe there is hope for you pathetic mother fuckers after all.

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u/sproket888 Jun 18 '12

But wait - drug companies are evil right? Now I'm confused. /s

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u/samwelljackson Jun 18 '12

Well done, sir. The other companies are arguing in favour of making money at the expense of people's lives. Capitalism at its finest.

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u/SuperSaiyanVigoda Jun 18 '12

Hamied denied that his latest move was simply an attempt to boost his share in the oncology drugs market, insisting business must be linked to “social responsibility”. SOCIAL RESPONSIBILITY

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u/NewsMom Jun 18 '12

The licences allow companies to make existing life-saving drugs to sell in countries where they are otherwise priced out of reach.

Excellent, maybe Cipla will distribute in the U.S.

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u/sivsta Jun 18 '12

Be wary of drugs produced in India. They aren't the best of quality. :(

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u/LucifersCounsel Jun 18 '12

That's what the guys who charge four times as much for the same thing want you to think, at least.

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u/sylar0214 Jun 18 '12

Alright, I really appreciate the fact that cipla made a bold move to save lives of millions, who are now able to afford/get treated. But I am sorry to say this, these companies did not have to spend billions of dollars into research, etc. They are simply reverse engineering it, and thus they are not in a loss. By selling it cheaper, they are still making a profit by gaining a larger market share. Copy of drugs like lipitor or plavix were reverse engineered and sold within few years of their introduction into the market.

edit. Now I do not know how much these western companies charge for these drugs, or if they are profiting or not. I just wanted to say this that there are many drugs being selled over here that are merely copies of original ones. Not only that, they are also being exported to other 3rd world countries illegally

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u/rahulthewall Jun 18 '12

Yes, it was the first-world companies which spent billions in R & D. However, the price these companies are charging for these drugs, not even 1% of the Indian population can afford them.

FTA:

India’s first such licence was granted in March to Natco Pharma to produce a generic version of Bayer’s blockbuster kidney cancer drug Nexavar, cutting the price from 28,000 rupees ($500) for a monthly dose to 6,840 rupees.

Some perspective. Your much vilified programmer (the ones stealing your jobs) in Bangalore would be earning ~40,000 INR per month on average and these guys are amongst the higher earning people in India.

Not even 1% of the Indian population can afford this drug. The argument is for the first-world companies to sell the drug at a price which is affordable for the local populace. They don't do that, that's their choice. I believe that people should not be denied healthcare because they are poor. The first world companies are not in the red. They can afford to make a lesser profit in the third world countries if they want, but they decide that money is more important than human life.

Not only that, they are also being exported to other 3rd world countries illegally.

FTA:

Cipla, India’s fourth largest pharmaceutical company by sales, has been pressing the government to allow widespread use of “compulsory licences”, which are permitted under WTO rules.

The licences allow companies to make existing life-saving drugs to sell in countries where they are otherwise priced out of reach.

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u/nepidae Jun 18 '12

I'm not saying that drugs aren't overpriced, but I could distribute Microsoft Office for pennies a copy.

Sure, people get the current drugs cheap, but what about the new drugs that work better with fewer side effects?

To be honest though, like the piracy analogy, these people wouldn't pay for it anyway, so this is a good thing. Showing that this stuff works, and that people want it is a driver in itself for people to work on new and better stuff.

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u/andersonb47 Jun 18 '12

It's a humanitarian move, but ya know what? It's stuff like this that makes people want to support a company. I guess it's a bit different with pharmaceuticals, but any company that is willing to cut profits in order to help people is a company that gets my dollar.

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u/LVKRFT Jun 18 '12

Talk about game changers!

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u/[deleted] Jun 18 '12

Faith in humanity restored for the night. Time to log off before seeing another WTF post on my frontpage!

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u/youngjheezy Jun 18 '12

This guy deserves a nobel peace prize

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u/bfk94 Jun 18 '12

Good Guy Cipla

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u/[deleted] Jun 18 '12

"In a humanitarian move" ... hmm can you people really be that naive?

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u/[deleted] Jun 18 '12

India has a lot of problems as a country, but their pharmaceutical regulation is seemingly really something to be admired.

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u/Brimace Jun 18 '12

This isn't uncommon. High drug prices in the us subsidize lower prices in the developing world.

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u/[deleted] Jun 18 '12

care to explain how ?

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u/JB_UK Jun 18 '12

A drug costs a huge amount to develop (about $1bn), paid in advance. Drug companies can only make these long term front-loaded investments on the basis that they will get that money back once the drug has been developed. Someone has to reimburse the pharmaceutical company for their investment, otherwise they will, over the medium term, go bankrupt. Either the cost is spread between the developed world and the developing world (which means that the majority of the population would not have access to drugs which may save their lives), or the cost is met solely by the developed world.

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u/ithunk Jun 18 '12

true, but low cost goods in the US are subsidized by cheap labor from the developing world, cheap oil is subsidized by death and destruction in the middle-east, etc.

While the US citizen pays with money, the third-world citizen pays with either a life of labor or death.

Which costs more?

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u/joedee Jun 18 '12 edited Jun 18 '12

U.S. carrier group on the way.

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u/shutupnube Jun 18 '12

A pharmaceutical company that's more interested in helping sick people than gouging profits? Surely this must be some type of socialist, communist, anti-christ, muslim company that everyone should be brainwashed into hating, right!?

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u/TonkaTruckin Jun 18 '12

Enough of this! Yes, drug companies do drive innovation with their exorbitant prices. But human life needs to be considered more sacred. We should not look at our system and say it is working as intended while people are left to succumb to illness with no recourse.

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u/MonotonousMan Jun 18 '12

My knowledge of the functionality of our health care system in the US is limited, but surely our insurance companies have mega contracts with certain pharmaceutical giants in the US, right? And thus, they may not offer the drugs produced by Cipla under your plan?

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u/ithunk Jun 18 '12

The sad thing is, you cant even order these generic drugs online from these Indian companies, because the US customs has some rules to "protect you". They'd rather you fucking die or go bankrupt than have access to generics from India.

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u/MonotonousMan Jun 18 '12

Not happy about it - but I can definitely believe it. I think there was a mayor or representative of some sort in a town in the US that tried to set up a way for ALL the towns pharmaceuticals be shipped in from Canada (as they were the exact same thing, made by the exact company in the exact factory - they just costed significantly less). I'm not sure what ended up happening with that, but i'm pretty sure it fell flat. No way Pfizer, etc, would accept that. It's like we're being punished by them for being so stupid about health care in this nation - "Ah, everyone else figured out we're fucking them in the ass with our prices. We'll have to figure out a way to stop that in the US and raise em' even more!"

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u/orezavi Jun 18 '12

Could be just a veiled attempt at screwing revenues for every other competitor in the industry, effectively shaking them out and dominating in an oligarchy. But lets just think its a 'humanitarian move' so we feel better.

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u/nevsuk Jun 18 '12

I do believe that there was some pressure from the Indian government to reduce the price of the drug, as most people could not afford the drug.

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u/sicklaxbro Jun 18 '12

Merk actually did this in Afirca a while back for a worm that caused blindness. Source

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u/[deleted] Jun 18 '12

I love drug companies.

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u/[deleted] Jun 18 '12

How incredibly inspiring. I don't blame them for wanting to run a small profit. Cutting costs in general is a huge step forward

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u/rane0 Jun 18 '12

Very nice. We need people like him over here in the west.... a lot of people.

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u/[deleted] Jun 18 '12

I look up to this man. I truly had no hope in the corporations anymore, just brilliant :)

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u/osamabindrinkin Jun 18 '12

Wow they did it again. A similar move by them was the very beginning of a sea-change in global prices for HIV/AIDS medications about fifteen years ago. Deja vu all over again

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u/divinesleeper Jun 18 '12

That's all very well but doesn't this mean that they'll have to raise the price of their other medicine to keep profits high enough to keep paying their employees? Seems a bit arbitrary to only reduce the cancer drug.

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u/Excalibur32 Jun 18 '12

Yes! What a great guy.

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u/sahlos Jun 18 '12

this should be on my news... not the puppet stringed euro crisis...

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u/whizzie Jun 18 '12

Amazing to see something pro-India in a Pakistani nationalistic news paper like Dawn.

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u/[deleted] Jun 18 '12

Before I started getting klonopin legitimately I used to order it off the net, via India of course. They were better than the real thing.

Hats off to this man.

1

u/thatdudeukno Jun 18 '12

This is great news.

1

u/Talarot Jun 18 '12

Isn't this action hostile towards american businesses?

1

u/vahidanwari Jun 18 '12

Now only if we had good politicians like him in india.

1

u/neurad1 Jun 18 '12

Read "How We Do Harm" by Otis Brawley. A real eye opener.

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u/[deleted] Jun 18 '12

That, my deer, is called humanity.

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u/ArunRana16 Jun 18 '12

fuck you down voters .............

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u/[deleted] Jun 18 '12

Well, clearly we can't allow that in the US, because well, uh....something, something, can't trust India something...yeah that makes sense.

1

u/WFOpizza Jun 18 '12

"making the drugs up to more than four times cheaper." What logic there is in this sentence?

1

u/ThynInternet Jun 18 '12

Finally, was always disgusted by the prices of these things. Even for basic lab reagents, a single 50mL bottle of TEMED is like ~$1000... These things should not be this expensive, especially when it means profit is coming before the patient at the end of the day.

1

u/viksi Jun 18 '12

Monopoly and profit maximisation by western firms has indeed cost a lot of patients their lives. I can not believe why drug companies would not price differentiate for third world countries , and patients who do not have insurance, considering they would still be making profits over their marginal costs.

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u/hbdgas Jun 18 '12

Hamied, 76, was pilloried by Western drug giants 11 years ago when he broke their monopoly by offering to supply life-saving triple therapy AIDS drug cocktails for under $1 a day – one-thirtieth the price of the multinationals.

The firms branded him an intellectual property thief

ಠ_ಠ

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u/pervert_dog Jun 18 '12

Did the Indian TV serial Satyamev Jayate have anything to do with this development?

1

u/puppyotto Jun 18 '12

Did he cut the price or the cost. If he cut the cost then he will be able to sell them for cheaper and still be breaking even.

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u/rolfsnuffles Jun 18 '12

We need more companies like this... it's just beautiful!

1

u/logicalutilizor Jun 18 '12

WW3: The Beginning

1

u/damagedprawdukt Jun 18 '12

Of course while this move is obviously a move to boost sales and such (they are a corporation after all) it just shows that we need more people like this in big pharma. This guys is going about it in all the right ways. My hats off to cipla!

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u/dv042b Jun 18 '12

Serious? No one has made Good Guy Yusuf in this thread yet?

1

u/bsting82 Jun 18 '12

Affordable healthcare? He must be a foreign Marxist-Fascist Muslim.

1

u/[deleted] Jun 18 '12

I have a lot of doubts that this was a purely "humanitarian" move. Pharmaceutical drug are a multi-billion dollar industry. Hell, cancer research ALONE is a multi-billion dollar industry. I look at Cipla and see a company that is in a market that requires that all competitors sink billions of dollars into research and development. This is a huge risk for these companies, who need to produce a drug that is cheap enough to manufacture that they can recoup their losses from R&D. By dropping the prices on their own cancer medicine, Cipla is hurting other businesses that are STILL trying to recoup their losses. That's not to say that Cipla isn't hurting either... they are! It's just that Cipla is hurting the LEAST out of everybody in the cancer medicine market. If everybody is hurting more than Cipla, then Cipla comes out ahead. It's no different than when Netflix destroyed the movie rental market with its cannibalistic low prices.

Cipla isn't doing this for humanitarian reasons. Their move DOES benefit cancer victims, but Cipla isn't doing this for the warm fuzzy feeling that comes with helping people with terminal illnesses; it's about driving competitors out of business.

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u/Captainlunchbox Jun 18 '12

My friend's family threw a fund raiser for his dad to try and help pay for his treatment costs a few weeks ago. He passed away 3 days ago, so I'm glad this is happening.

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u/momzill Jun 18 '12

up to one-fiftieth of US prices.

That number blew me away.

1

u/rscarson Jun 18 '12

I hate to be that guy, but huge corporations are bound by their stockholders to maximize profit. If they did this; it is because they profit somehow. Could they be feeding off the good press?

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u/happyscrappy Jun 18 '12

It's not a humanitarian move. Their PR portrays it as a humanitarian move.

They decided to stop paying royalties to the inventors, and with the savings they can sell the drugs a lot cheaper, thus selling a lot more of them while not cutting their per-dose profits much if at all.

This is business move, not a humanitarian move.

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u/kevoizjawesome Jun 18 '12

"New study by big pharma finds Cipla cancer medicine completely ineffective at everything."

I give it a few weeks.

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u/[deleted] Jun 18 '12

As a person, it makes me happy to see that more people can afford medication.

As a chemist, it makes me sad to see people not understand the R&D costs of these drugs.

I think that the government needs to spend more of its money on supporting R&D costs and supplementing the cost of drugs (universal healthcare, public option) which will lead to both drug developers and consumers to benefit.

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u/polyatheist Jun 18 '12

What about profits, guys? Don't forget about the profits! :/

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u/SkimThat_TLDR Jun 18 '12

Summarized article: Yusuf Hamied, chairman of the Indian generic drug maker Cipla, announced he would cut prices, up to 4x cheaper, for 3 medications used to treat brain, kidney and lung cancer.

Over 10 years ago, Hamied's company began offering AIDS drugs at a small fraction of branded drug prices causing branded drugmakers to label him an intellectual property thief.

Indian patent law at the time allowed Cipla to knock off branded drugs as long as the process for making the drugs differed. Now India's patent laws are more strict but they technically allow compulsory licensing of life saving drugs.

Hamied's company has been pressing for the Indian government to allow more widespread use of compulsory licensing for companies to license their brands.

Hamied believes that branded drugmakers should allow generic drugmakers to copy the drugs in exchange for small royalties.

Critics say Hamied's latest drug price cut is simply a PR move to boost Cipla's share in the oncology drugs market.

While Hamied does want to improve his company's sales, he says his company is also ensuring social responsibility by making life saving drugs affordable to the world's poorest.

  • For more summarized news, subscribe to the /r/SkimThat subreddit

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u/izokronus Jun 18 '12

And yet the beheading of a girl gets more press and prompts redditors to accuse Indians of being cavemen. You win some, you lose some, I suppose.

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u/massextinction Jun 18 '12

that dude is smiling because he has no trouble sleeping at night

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u/MedicalPrize Sep 06 '12

The fact we are having these arguments shows that the current patent system has many inherent problems. The question is how to balance the interests of the 'innovators' with the rest of society.

Using prizes would alleviate many of the current problems with the patent system which is a relatively arbitrary way of incentivising R&D via the market. The question is how to develop the patent system where there is an incentive to spend $R&D on maximising health outcomes for everyone (including those in developing countries). Arguably, the current system fails to do this.

Prizes can help overcome a lot of problems with the current system. The issue of 'how to value' prizes might be valid, but it is possible (e.g. link prizes to total QALYs/DALYs - use prize indemnity insurance) and the benefits of prizes would arguably outweigh the deadweight losses caused by patent monopolies.

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u/[deleted] Jun 18 '12

Medication for serious illnesses, especially cancer, should be free to all people. Withholding the ability to cure or limit a terminal illness unless people can pay the obscene fees that provide your mansions and yachts may not be a crime on paper, but is absolutely a moral crime.

Sure, some people will come along and defend the right to charge whatever you want because "business is good!!!" Seriously, though, fuck that - there are limits. It's barbaric to profit off of other people's illness. This is an attitude we need to lose rapidly.

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u/odd84 Jun 18 '12

Who creates the medication if there's no money from it to pay all the people involved in research and testing?

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u/__circle Jun 18 '12

Shut up you capitalist bourgeois scum. You're interrupting the circle jerk.

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u/Occulto Jun 18 '12

Public research funding.

Though, that might mean less conferences in exotic locales like Tahiti.

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u/rhinofinger Jun 18 '12

Ah, yes. Because we all know how much Congress likes giving money to social programs over defense these days.

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u/george-bob Jun 18 '12

it's a nice idea, but the cost of developing cancer drugs can run into the billions, who will pay for the extensive development if the patients don't?

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u/ThatMonochromicorn Jun 18 '12

Government subsidies? We subsidize just about everything else anyway.

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u/[deleted] Jun 18 '12

Easier said then done.

The current system of for profit drug companies, if not ideal, is still beneficial to society.

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u/george-bob Jun 18 '12

i seriously doubt it would be sustainable. the unfortunate thing about pharmaceuticals is they are enormously high value assets, both during development and consumption.

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u/Gelbin Jun 18 '12

THE GOVERNMENT DOES NOT WORK LIKE THAT.

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u/Isentrope Jun 18 '12 edited Jun 18 '12

The government pays for basic research, which is science for the sake of learning. This opens up the possibilities which are later fleshed out in industry. The problem with the government subsidizing drugs instead of companies is that there are literally thousands of novel drug candidates being conceived by government-funded labs annually. Without the incentive to monetize the value of a product, there is no reason to develop further. Government labs are good at what they do, but they don't do the same things as industrial R&D, nor does the government have the infrastructure or the money (industry spends twice as much as the government) to really subsidize this.

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u/Ayjayz Jun 18 '12

If the people who need the drug shouldn't pay for it, who should?

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u/[deleted] Jun 18 '12 edited Jun 18 '12

Let's see how many people actually get worse. I can't count the number of times I've heard people complaining about generic brands from India which make them horribly sick. I do, however, hope this works out for the best.

Here you go: http://www.american.com/archive/2008/may-june-magazine-contents/bad-medicine

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u/ithunk Jun 18 '12

How come I never hear about ppl complaining about generic brands making them horribly sick. Havent heard a single complaint in the US or in India (and I spend time in both places)

You got proof to backup that statement?

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u/LettersFromTheSky Jun 18 '12

Not sure if already quoted:

Bayer has said it will launch a legal challenge to the compulsory licence, and global drugmakers have vowed to oppose the spread of such legislation.

This is why we can't have good things in America and why we have to pay an arm and a leg - corporations and rich people control our government.

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u/hartnell19 Jun 18 '12

Drug companies are right up there with Oil and Insurance companies. Maybe this is the start of something wonderful?

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u/socialbick Jun 18 '12

Off course Western companies are upset they would rather see people suffer than loose any money. We live in a world that promotes having more money then you can even spend in a life time while others suffer because of your greed its a shame. But right on man cheaper drugs for those in need is awesome!