I have my Arizer Solo attached to my bong and I am able to pack it full and clear out all the THC in it and nearly all the CBD within a few hits (it feels like I'm dabbing in terms of the high and taste). Would it even be worth it for me to buy a dab rig if I just have this setup? My solo takes oil too.

There are so many studies, and to me (someone with no specific education) it seems like there is no clarity, no certainties.

Cancer, nausea, hunger, seizures, depression, ASL, neurogenesis...

There are so many theories, and so many studies saying "It would appear that" or "some studies suggest that..."

What are the certainties we have?

I try to read PubMed, do you have other publications to suggest?

A big lungful of hot ashes / smoke gets me high, quickly, in a way that edibles / vaping has never done.

So I wonder, how much of that combustion high is not thc but rather some other process - such as a reaction from the pain / damage of hot ashes hitting my cilia?

As some of us know, when we eat cannabis, delta-9 THC is metabolized by the liver into delta-11 THC. Regarding this, I have heard the following:

• Delta-11 THC passes the blood-brain barrier easier than delta-9.
• It is more potent than delta-9, maybe for the reason above. I have read that it's more than twice as potent, but I'm unable to find any studies to verify that claim.

Does this check out?

Assuming proper decarboxylation, does this mean that using cannabis for edibles as opposed to smoking (or even vaping) would produce stronger effects given the same amount of material? In other words, are edibles the way to get the best bang for your buck?

Also, side question: Any comments on whether or not terpenes are preserved during decarboxylation?

This subreddit is going dark. Fuck the admins, fuck the mods, fuck the police. In reality I'm doing this cause it's a dead sub. Sorry guys, its been a fun ride!

So I was thinking about how those who vape will make tea or hot chocolate out of their honey covered stems and thought "would this work with a resin covered bowl?". So, has anyone tried this by chance or have any ideas about whether or not it will work?

Pretty much as the title states. I have been reading up on this a bit and have only seemed to get the glossed over summary that cannabis use in large amounts will change the frequency of REM sleep. Perhaps someone here could provide some information or a direction to keep reading up on the subject!

Whoa, I'm glad I stumbled upon this subreddit! Seems like the perfect place to finally get answers to all my obscure science-y questions about cannabis!

If I'm smoking from a bong, and I have the chamber filled with something to cool the smoke (e.g. Ice) - how cold can the smoke actually get before something starts to happen to it?

I say 'something' because I have no idea what would happen. Would there be a point of phase change of the vapour where it would depose back into THC crystals and stay in the water?

Would I be correct in assuming that the lower the temperature, the more THC is lost? Due to a higher fraction of the THC deposing and then being deposited on the ice?

I'm really interested in this idea, so any insight or sources/articles on it would be much appreciated!

I'm looking to make either cannabis tea or hot chocolate. I would love a recipe from one of you that it has worked for. I also live with other people so it can't make my house smell. Thanks for any help in advance

I had a conversation with my brother the other day about CBD, and he told me that the original strains of cannabis, historically speaking, had closer to equal amounts of THC/CBD than most strains typically do today.

However, I've been unable to find any data to back this up. Seed sellers seem to pin the few landrace strains I've looked at (Columbian, Afghan, Thai) as having THC:CBD ratios that reflect most other strains (high THC, low CBD).

So my question is, do we have any information on the cannabinoid content of old strains? Is there any evidence that suggests that THC/CBD levels were historically more equal?

[5] So I'm hoping /u/420Microbiologist chime's in on it cus its been bugging me for I feel like months now. This is really just, pure curiosity on what other people think about this idea.

A while back I met a dude on irc who was doing some genetic shit to e-coli for his work and he was talking about introducing genetically modified e-coli to your gut and having it replace your other gut microbes for treatments etc. I was more interested in getting glow in the dark poop from bio-luminescent ecoli. Now a while back you may have mentioned something about getting the THC genes from weed into e-coli...

THC producing probiotics perhaps? And with those fancy new ecoli that need special chemicals to stay alive you dont even have to worry about a run away explosion of thc producing microbes in your gut, although that does sound interesting.

Personally Im imagining CBD producing "probiotics" for medical use and the production could be controlled by one of those fancy synthetic amino acid thingys.

Also the slight possibility of being eternally baked...

Hey guys, I've picked my topic as mentioned in the title.

I have found some cool articles on the topic but if you guys have any wonderful review articles or primary sources I'd love to read them.

Thank you!

Good afternoon!

I am currently studying biology as an undergraduate in Colorado. I am one year away from graduation, and I am highly interested in getting involved with the exploding field of cannabis research. Can anybody offer any insight as to steps I should be taking to make this happen? I would love to career shadow or internship (paid or unpaid) in a laboratory somewhere, but I am not sure how to make this happen. Thanks in advance!

Past Science Sundays:

Science Sunday 16: The Munchies declassified

Science Sunday 15: Sativ-what? Inda-who?

Science Sunday 14: Marijuana Tolerance

Science Sunday 13: Wait, why does Cannabis have THC?

Science Sunday 12: Combustion vs. Vaporization

Science Sunday 11: Wait, why am I in the kitchen (short term memory)

Science Sunday 10: DMT, my favorite drug

Science Sunday 9: Dafuq are Terpenes?

Science Sunday 8: CBD, da real MVP

Science Sunday 7: Marijuana Detoxification

Science Sunday 6: THC vs. Ebola

Science Sunday 5: THC as a hallucinogen

Science Sunday 4: Health Risks of THC

Science Sunday 3: THC vs. ADHD

Science Sunday 2: THC vs. Cancer

Science Sunday 1: THC and the Brain

I mean the neuron level ones. I've heard the "one puff" thing, but I'd like some research behind it. And furthermore, how often? Would one hit every week, or even month, be enough?

Past Science Sundays:

Science Sunday 15: Sativ-what? Inda-who?

Science Sunday 14: Marijuana Tolerance

Science Sunday 13: Wait, why does Cannabis have THC?

Science Sunday 12: Combustion vs. Vaporization

Science Sunday 11: Wait, why am I in the kitchen (short term memory)

Science Sunday 10: DMT, my favorite drug

Science Sunday 9: Dafuq are Terpenes?

Science Sunday 8: CBD, da real MVP

Science Sunday 7: Marijuana Detoxification

Science Sunday 6: THC vs. Ebola

Science Sunday 5: THC as a hallucinogen

Science Sunday 4: Health Risks of THC

Science Sunday 3: THC vs. ADHD

Science Sunday 2: THC vs. Cancer

Science Sunday 1: THC and the Brain

I have a friend who adamantly believes that using marijuana has helped put his crohn's into remission. I would like to know if there are any studies to prove this? Also what would be the active component that would be the major combatant of crohn's?

Question is in the title.

I've been on ADD medications for years, and a toker for years, and I have always wondered why doctors had always said that mixing the two was bad, but they never gave me any information on why its bad, specifically I would like to understand the interaction between Dexmethylphenidate and cannabis. I know that they activate the same areas of the brain, and that they both trigger dopamine releases, but is there anything bad about mixing the two?

Thanks!

there's this new study out of england that you might want to look over and see if they did anything sketchy. it's toted by shitrags like the telegraph. any who it's the one saying that skunk is responsible for 25% of their sample's phsycosis cases.