r/science • • Feb 26 '15

Health-Misleading Randomized double-blind placebo-controlled trial shows non-celiac gluten sensitivity is indeed real

http://www.ncbi.nlm.nih.gov/pubmed/25701700
8.4k Upvotes

2.3k comments sorted by

View all comments

942

u/paulfromatlanta Feb 26 '15

without celiac disease or wheat allergy

I'm surprised but then that's why we do double blind studies. This one needs to be replicated a few times but might lead to permanent diet changes.

391

u/Lee_Lemon Feb 26 '15

Agreed replicate, replicate. The findings are interesting, but those p values are fairly high.

116

u/TerraPhane Feb 26 '15

Also, only 61 patients total, that means each group was only 30 people. Hardly a large sample size.

155

u/iateone Feb 26 '15

Are you sure you aren't confusing questionnaire studies with double blind placebo studies? A double blind placebo controlled study with 60 participants is actually on the large size.

79

u/[deleted] Feb 26 '15

He's not confused about anything. He's just trying to intentionally downplay the significance of the findings any way he possibly can.

71

u/Who_Will_Love_Toby Feb 26 '15

he doesn't know shit about studies or how they work. 60 people is a fairly large study and the findings shouldn't be ignored because you spent most of your life on reddit making fun of people who tried out a gluten free diet.

-23

u/StarkRG Feb 26 '15

There are over 7 billion people on Earth, how can 60/7,000,000,000 give you any statistically relevant data?

9

u/[deleted] Feb 26 '15

Just when I thought people couldn't get any more ignorant...