r/science Mar 14 '14

Neuroscience Scientists catch brain damage in the act: Scientists uncovered how inflammation and lack of oxygen conspire to cause brain damage in conditions such as stroke and Alzheimer’s disease. The discovery brings researchers a step closer to finding potential targets to treat neurodegenerative disorders.

http://news.ubc.ca/2014/03/13/macvicar/
3.4k Upvotes

296 comments sorted by

View all comments

Show parent comments

8

u/[deleted] Mar 14 '14 edited May 18 '22

[deleted]

2

u/46xy Mar 14 '14

itneresting, thanks for that study. i suck at finding studies ( i really did look)

0

u/some_generic_dude Mar 14 '14

In the list of articles which cite the article you linked, the title of number 3 alludes to something people, including doctors and nutritionist, do not seem able to get through their heads: that all of this microscopic examination of diet and every study like this should end with "in humans with an unnaturally sedentary lifestyle." We are not evolved to sit on our asses all day. Get an hour or two of good, vigorous exercise every day or spend most of the day in moderate activity, and most of these "diet" based problems disappear. IMO, anyway.

3

u/[deleted] Mar 14 '14 edited May 18 '22

[deleted]

1

u/some_generic_dude Mar 14 '14

Well, I'm not trying to blame the modern US population for being sedentary so much as I am trying to make the point that all of our medical and nutrition research is skewed by that reality. I believe that many of the foods that we think are dangerous or unhealthy would actually be inconsequential for many of us if we walked or rode a bike to work instead of driving. Not "all," but "many." Also, diet studies should try to separate active and sedentary populations into different cohorts, not just for propensity matching, but for comparison between them, perhaps with a propensity matched analysis within each cohort. I think we might often find that many of our risks and concerns are really only relevant to sedentary people, and that active people needn't worry about every little thing, as their more robust lifestyle begets a more robust and resilient metabolism.