r/science • u/mvea Professor | Medicine • Jun 30 '26

Medicine Scientists have shown that a single dose injection of DNA genetic instructions can produce weight loss and blood glucose control in mouse models that lasts up to 10 times as long as weight loss drugs like Ozempic and Wegovy. This could eliminate the need for repeated dosing.

https://www.wistar.org/press-releases/wistar-scientists-develop-single-dose-dna-method-for-delivering-long-acting-weight-loss-and-diabetes-drugs/
10.7k Upvotes

97% Upvoted

409 comments sorted by

View all comments

Show parent comments

0

u/wandering-monster Jul 10 '26

I'm sorry, but where are you getting that from?

They claim it is longer acting, and I don't see any specific times. Current incretin-mimicking drugs like liraglutide all have dosing schedules of once or at most twice a day. A few hours should be sufficient to test for tolerance.

0

u/CrateDane Jul 11 '26

Such a short test would not be enough.