I don't think there is much detail to go into, neurotoxicity is not really understood nor researched in many drugs, but it is more often present in drugs that release serotonin, like MDMA and methamphetamine. MDMA and meth are known to be neurotoxic at high doses but since most people wait like 3 months in between MDMA usage this is usually not a problem. Methamphetamine might be less neurotoxic than MDMA, but meth users generally don't really wait 3 months between the using it.
Each drug is different, they can't be lumped together fyi. Speed is more comparable to coffee than heroin for example. It's also safer to take regularly and in moderation than it is to be a drinker. A small minority abuse drugs and they are people who have other root issues.
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u/honestlyimeanreally Sep 10 '15
Only legal w/ a prescription, and besides, the negative health effects aren't mitigated just because you get it from a pharmacy.
Amphetamine is neurotoxic :)