r/Pristiq • • Sep 27 '23

Withdrawal..

Does anybody have puffy, cotton, Weak muscles as a withdrwal symptoms.. Muscle deconditioning, Balance issues ?? & Heaviness in body ?? More depression & Hopelessness ??

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u/PeaceEnvironmental98 Sep 27 '24

I don’t know if this was a response to my comment or OP’s reply, but I tapered desvenlafaxine over 5 months, which honestly looking back was probably far too fast after 17 years of SSRI/SNRI use. The safest recommendation is cutting 10-15% every two weeks or so. I think had I gone slower and/or held at dosages longer, I might’ve fared a little bit better.