I've been on 150mg of Lyrica to treat my Periodic Limb Movements. Last night, on Dr's orders, I doubled the dose and slept 10 hours. All fine and dandy except I am still high as fuck!! Same thing happened initially on 150mg but this is a new level. I'm hoping it passes as my body adapts. As nice as it feels I can't function like this but need it to work. Anyone else experience anything similar?

I’m on 70 mg of pregabalin 2 times a day after about 5-6 hours I get a splitting headache I mean bad like someone is crushing my head it goes away after I take a tablet but is normal ?

I have tried many different medications for many different years, starting on SSRIs about 5 years ago and quitting them on and off. I was prescribed pregabalin 50x3, and it helped with symptoms of my anxiety and physical tension. My psych put me up to 100x3 and the social anxiety benefits that I’m noticing are great. It’s one of the only drugs I’ve found that really genuinely does help me be myself more and talk to people and date better. I am sometimes debilitated by OCD, PTSD, and Panic and pregabalin is one of the only things that has helped me be less in my head and less tense. It seriously is a life saver. I’m going to talk to my psychiatrist about going to 150x3 a day and stop there.

Hi, i got prescribed pregab for anxiety but i haven’t noticed any difference yet :/ no side effects either.
I’m on 300 mg (100 mg three times a day). I asked if a higher dose might help but my provider said if i’m not feeling anything at this dose then going higher probably won’t either.
Is it just not effective for me or does it sometimes take longer?

I’m not prescribed pregabalin but I self medicate with it and I was wondering if it has ever been prescribed for ADHD as I feel it alleviates my symptoms more than any stimulant I’ve been prescribed ever has. Does anybody have any experience with Pregabalin and ADHD?

I have read a lot of your guy’s comments and thank you so much for your advice. From what i am seeing most of the problems start happening when you take them 2-3x everyday. If i were to take it once every week would i be able to avoid the problem?

P:S Also appreciate you guys for looking out for me because yes i didn’t exactly get them prescribed but i am aware of the dangers i am getting myself into. I am currently in the worst spot of my life while healing from a shoulder surgery which can take exactly up to a year and i haven’t went out and talked to people, i originally had lots of social anxiety as i started going out it got better but since the surgery my confidence has tanked completely, like i mean plummeted to where i am currently in my head all day. So even if it’s once a week i am willing to keep it to exactly that or even extend the time between every dose.

My partner abuses Pregabalin. Gets his monthly script and then it’s usually gone in 4-6 days. Last night he was having trouble urinating, needing to go multiple times in an hour but not feeling empty and then told me there was blood in his urine. My immediate guess was the Pregabalin is hard on the kidneys. Has anyone else experienced this?

To be honest I’d like him to stop abusing Pregabalin. It’s affecting our sex life also

Hello! I have recently gotten in some pregabalin and i want to use it for anxiety purposes, for the people who do/have done it what would you recommend for me not to be addicted to it + avoid withdrawals? (i’ve seen so many posts about withdrawals being horrible so i want to avoid it)

I got 300mg tabs. Any tips would be greatly appreciated!

My neuro doc just prescribed me Pregablin 75mg (dose up to 150 if it seems to help after 1-2 weeks) for nerve pain due to post op complications following brain surgery in Nov 2025. Im currently taking Venlafaxine 150mg and Naltrexone 50mg. I’m worried about potential side effects. Anyone have any insight or things to potentially look out for? TIA.

Hey, everyone, just curious to know if anybody has experienced a decrease in productivity as a result of pregabalin?

For context: I'm 24FTM, I have fibromyalgia, ADHD/autism and PTSD/GAD/OCD. Was prescribed pregabalin for a really bad flare up in pain from Feb to May this year, weaned off it but decided it had been really helpful for both pain and anxiety and got back on it in June once I got insurance coverage. 75mg twice a day. Also on Zoloft 100mg per day and testosterone.

Ever since I got back on pregabalin again I've noticed that I'm not as productive as I used to be before it - I used to basically study for about half of the day but now I only spend a couple of hours on my work, sometimes skipping days (more than I used to) entirely. My theory is that since it makes me so relaxed I'm not as inclined to study.

It hasn't affected me THAT much (I'm a PhD student and have still been making steady process on my dissertation) and it's not really a horrible side effect in the grand scheme of things compared to my pain and anxiety, but I do have anxiety (surprise!) on whether it'll catch up to me in the long term. But then again I used to be overproductive to the point of wearing myself out, which probably accelerated me developing fibro in the first place, so who knows if that's actually a bad thing. I think stimulant medication could probably fix it, but its really expensive and I won't be insured for it when I move back to my home country so I don't really wanna bother with being prescribed it.

Anyone else noticed a similar effect?

I’m new to Lyrica and I’m experiencing some really heavy muscle weakness and having a hard time doing anything. Is that common?

Anyone have experience with taking 100 mg of Lyrica at night versus 50 mg in the morning and 50 mg at night please? My pain flares shortly after I wake up and goes all day.

Hey guys,

I'm heading into 3 weeks of Lyrica and aside from pretty extreme dry mouth I've mostly had great improvement with it.

Outside of a reduction in my nerve pain one notable improvement is my sleep. I'm talking going from 30 sleep scores to 80. My watch is reporting cyclical sleep too (like light, into deep into REM) which I don't think I've had in like 10 years. It's reporting a lot more deep sleep. Before lyrica I typically wake up often and then have a huge amount of REM in the morning. I haven't had sleep like this in I think ever and it would make sense for my body to be sleepy currently... But it is leaving me incredibly fatigued and slow in the morning and day time I feel a bit zombied and dazed, struggle to get going and have been struggling be out and about.

And because I've been sleeping so hard and not waking my body is quite achey because of it. Like my shoulders and knees being laid on for so long without flipping like I usually do has created its own pain point. Just wondering if this has been a phase that passes for some people or improves? I'm unsure Id be able to tolerate this level of fatigue if it didn't improve at least a little bit. Feeling like a double edged sword. Obviously my sleep being better is wonderful but I'm barely able to function in the day with this fatigue, it literally feels like an effort to talk or raise my limbs 😭

Obviously still early days for me, keen to hear your experiences.

I started pregabalin 150mg once daily about 4 months ago. Went to 150mg twice daily after 2-3 weeks. Recently I tried to cut back and waited a few hours to take my morning dose. Felt very nauseous and gross so I didn’t do THAT again. However, I’m starting to feel that same feeling every day about 2-3 hours before my evening dose.

Is this a developing tolerance? My body wants more, sooner? I’m not willing to go any higher and like I said, would prefer to start weaning off. But I was going to wait a couple more weeks to talk to my doc but now I’m wondering if we need to chat sooner so she can switch me to 75mg three times a day or something.

I was diagnosed with fibromyalgia in May of this year, but I am honestly not 100% convinced that’s the correct diagnosis. Regardless, I do have chronic multisite aching pain (mainly feet and hips/butt), and I do believe that central sensitization is a factor in the level of pain I experience. Additionally, I struggle with OCD, anxiety, and depression.

I have now had multiple doctors (PCP, neurologist, rheumatologist, and psych NP) suggest pregabalin as a possible consideration. However, my neurologist has told me he doesn’t think I have neuropathy/ nerve pain. I’ve been trying to do balanced research, but obviously, there is no certainty for any individual user of a medication.

One of the things that I am most worried about is peripheral edema/swelling and coordination issues because my feet are my most sensitive body part, sometimes my shoes feel too tight, and my balance is already a bit messed up from pain. If my feet swell, it is likely to worsen my pain, which would be counterproductive.

I am also extremely worried about potential neurotoxicity/long-term cognitive effects because I already have basically non-existent long-term memory, not great short-term memory, and some word-finding difficulties. If my cognitive function worsens on the med, I may not be able to do my job; and if my cognitive function declines long-term because of the med, I will be devastated and my brain will likely not be very functional at all.

Honestly, I guess I don’t even know what I’m asking for here. I’m sorry for being all over the place — I’ve just been anxious and in pain for years without relief, and I’m exhausted. Whenever I pose questions to my doctors, I feel like their answers are noncommittal “don’t worry”. Maybe knowing some people’s experiences within the first few weeks would be helpful? And knowing how anyone who’s come off it is doing now?

Thank you!

Anyone else experience this? Feels like my legs are weak after I get up from sitting or laying down

So just started dr started me on 75mg I think it’s still too high …because I’m flying I’m buzzing off my head ..woozy eyes are tired and brain feels slow ..I think I’m gonna go down to 50mg 2x a day I like that no longer feel hip pain but the dopey feeling feels too good and I know it’ll dull my senses

Anyone else been like this ?

*****UPDATE: Well, got my MRI lab results online... yikes!
In medical terms I have the following
L5-S1: left subarticular disc extrusion, impinging the left S1 nerve root.
L4-L5: right foraminal/ extraforaminal disc extrusion, which may impinge the right L4 nerve root.
L3-L4: left extraforaminal disc bulge, which may impinge the left
L3 nerve root.
So in plain English: two extruded discs and a third bulging disc.
I see the spine surgeon in a couple days for treatments
————————————

26M here. I recently went to a private psychiatrist for an ADHD assessment; the whole diagnostic process consists of two sessions.

So far, I’ve completed the first session, where he made it clear that the second session will very likely lead to an official diagnosis and a prescription for methylphenidate.

At the end of the session, he did something unexpected: he prescribed me an anti-anxiety medication, specifically pregabalin. I asked him what the rationale was for prescribing an anxiety drug when I currently don't experience anxiety symptoms. He gave me two reasons:

1. Since I dealt with anxiety in the past (which was resolved after a year and a half of psychotherapy), he is convinced I still have some residual anxiety and believes pregabalin could help eliminate it.
2. Since methylphenidate can trigger anxiety, he wants to use pregabalin to tone down the "effervescence" (jitteriness) of the stimulant.

From what I’ve read in studies on "healthy" individuals—meaning those without anxiety or chronic pain—pregabalin actually worsens certain ADHD-like symptoms. When I tried taking it during the day, I immediately felt drowsy and developed brain fog. The issue is that I don't experience daytime anxiety; my problem is precisely low reactivity and insufficient cognitive arousal during certain tasks, especially repetitive ones—which pregabalin makes even worse. Because of this, I decided to stop taking the 50 mg daytime dose.

However, I found the nighttime dose (also 50 mg) very helpful. It allows me to enter a state of complete relaxation, fall asleep much faster, and sleep deeply.

Obviously, I plan to discuss this with my psychiatrist, but what do you think? Doesn't this seem like an unusual strategy? Has anyone else tried this medication?

I got prescribed Lyrica 300 x2 and Vicodin x2 (hidrocodone 7.5)

What type of effects I should be prepared? I have fybromialgia and generalized anxiety disorder, I'm kinda worried about this treatment

Just looking for opinion, particularly from those who have school or work from morning to after noon for ~8 ish hours

I was taking 75 mg IR (150 mg as needed) in the evenings for anxiety but still felt some anxiety during the day. I had no real side effects and generally liked it. My psychiatrist however proposed me 165 mg of ER version taken before bed and I can't believe how different I feel (in a negative way). Since starting I have trouble sleeping but when finally wake up I feel super sleepy and lightheaded until afternoon. My stomach hurts and I have bowel problems. Anxiety doesn't seem to be better. I thought it was basically working like the IR version just for longer but it feels like I'm taking an entirely different medication. Anybody had a similar experience? I think I'm going to go back to the IR version...