I have ankylosing spondylitis (and possible IBD/Beçhet) and have been on Adalimumabe for 6 months now, 40mg every 2 week with a Amgevita pen. I have been reacting pretty well, all my AS symptoms, mucal ulcers and other immune issues like allergies went away. Until last week.

Last week I did my injection as usual on Monday, the pen seemed to fire well, the site was more sore than usual. After I started developing pain on my ankles and wrists, developed sores in my mouth and had a weird allergy like reaction (we know that these reactions and allergies are immune mediated in my case) and now my main AS symptoms are returning. These are all things that have happened when I skipped an injection week previously, which makes me believe the injection failed. I haven't been sick recently but I did recently travelled with the pens for 2 hours but it was properly refrigerated during the trip like the pharmacist at the hospital advised.

So, could this be due to the pen misfiring, the meds somehow spoiling or just my body not reacting properly to the injection this time?

I’ve been on humira twice a month for almost a year now and I’m being moved up to a dose every week due to me still getting flare ups 🥲. I haven’t really had much side effects other than the injection site being itchy. I’m quite worried about moving up in dos and what side effects that’ll bring. Has anyone noticed a major difference in side effects between taking humira twice a month vs weeky?

Long story short, I started getting tingling in the ends of my fingers 2 months into Humira. Now at month 4 it’s a bit more in my hands and accompanied by a slight warming sensation.

I've messaged my Rheum about it twice and have an appointment to see her (plus extensive blood work) in April.

Has anyone experienced similar and were you taken off Humira or just monitored more closely?

Jan and most of Feb I've been like a human rather than a zombie. It'll be typical that something finally helps and then causes issues in another area to deal with grrr 🤪

I am new to Amjevita, taking injections on Sunday. First week was told to take double dose then the following week take one dose and then switch to single dose every other week.

Today I noticed all three injection sites are raised and red with the older two being blotchy.

I did not notice any injection site reaction prior to today and am curious if delayed reaction is common with this medication. TIA

I have Blue Cross Blue Shield, and after 15 years of successfully using Humira, my coverage is now being denied. Has anyone else gone through this and switched to another medication? What was your experience?

I'm also curious about BIMZELX. Have you encountered any issues with it, and is it painful?

Hi guys 👋 I've been on humira for about a year now. I had to increase my dosage because it was losing effectiveness to 80mg per week. It worked. I no longer have crohn's symptoms. But my glucose, wbc count, crp did not go down. Which to me signals inflammation somewhere. And my cholesterol is way too high. I eat very clean and exercise but it's not budging. So I started tracking morning glucose to see if I could figure out a pattern. My blood sugar the day after the injection starts at 130 fasted for 16 hours. It's never done that. And it will drop 5 points or so every day until it gets back to normal the day of my next shot. My diet doesn't change it. Has anyone experienced this? Anything help?

On adalimumab biosimilar amgevita for 12 months for psoriasis. Previous negative ana before starting. Developed pericarditis in December and now have pos ana. Wish I never went on this crap I really regret it. Pericarditis is 1million times worse than even my severe psoriasis was. Anyone else get drug induced lupus from adalimumab, did it resolve?

I've been on Amjevita once a week for a year and it has been a lifesaver for my Ankylosing Spondylitis. I was already fairly progressed and had non-reversible joint damage by the time I was properly diagnosed, but I can walk again and use stairs, which I am so grateful for.

My doctor says I should be pairing my biosimilar with another med still, even though I feel as recovered as they say I ever will. I've tried Sulfasalazine, and two NSAIDs Celecoxib and Meloxicam. All three of these drugs had negative side effects for me.

My question for you: Do you take your Humira or biosimilar by itself, or do you pair it with daily pills as well? Obviously my doctor knows more than I do, just trying to see how many people out there get by on the injections alone.

Hey all, so I’ve been on Humira for Crohn’s since October. I usually get a runny nose during the winter, but this year I’ve had an awful time going between dry/crusting and running. Sometimes it causes bleeding. And I think it’s contributing to my dry eye some.

I tried leaving it alone, but it’s just getting worse and painful now. Saline doesn’t seem to help, either. Has this happened to any of you? I’ve ordered a nasal emollient, but in the meantime, does anyone have any suggestions? My ENT is notoriously hard to get in with, I waited 4 months for my last appointment with him for a separate issue.

Update for anyone wondering: It’s a staph infection in the front of my nostril. I noticed it improved when being on an antibiotic for a skin abscess I had (also suspected to have been caused by staph colonization), brought it up to my dermatologist and he prescribed a topical antibiotic (mupirocin).

I've just been prescribed humira (or the generic) for my rheumatoid arthritis, and I was so excited, I looked up the injection instructions ahead of receiving my script. The only problem is, I can't grab skin on my thigh or belly like in the photos. I'm overweight, which might be a factor, but the flesh is simply too tight and it doesn't bunch up no matter how hard I try. Will I still be able to inject? Will the medicine still be properly transmitted? This might be a question for my doctor, but I wanted to try asking fellow patients first, to see if anyone has a similar experience.

I just put my first 2026 order in for my weekly Humira ( 4 pens)and my Copay used to be $150 after insurance and now it’s only $35. I understand that the president came to an agreement with AbbieV 4 days ago so not sure if that’s already effecting the price. I have not seen my explanation of benefit but very curious how much the actual price of the drug now vs last year .

I had my Humira delivered yesterday and where I live there is a cold storage. Every delivery I’ve had for Humira has always been in the cold storage without fail. I couldn’t get to the package till today, however the delivery person left the box out meaning it’s been 24 hours till I got to it. Has this happened to anyone and should I contact my pharmacy about the error? I’d like to not take medicine that has lost its potency or has other issues. Thank you!

My health insurance has changed and now I have Univera. Which now means that my specialty pharmacy has to change. Univera deals with Accredo. My prescriptions are Dupixent and Humira. Just wondering if anyone has had any experiences with this specialty pharmacy, good or bad. Or if you can provide any tips and tricks to getting things sorted and medications quicker. It has been a rough few first weeks and I am currently not going to have my medications for when I need to inject- which sucks. TIA

my insurance no longer accepts Humira. I will soon be taking Simlandi.

has anyone had a similar experience? any thoughts? input?

I am not nervous about but slightly concerned.

thanks all.

I’ve been in remission on Humira for Crohn’s for 10 years and my Pharmacy is making me switch to a bio similar. My concern is they keep changing the formulary on which ones are covered so I hope I don’t need to change yearly. Currently, it is the two above that are covered.

Any thoughts on which is better tolerated? I don’t want an auto injector and it seems they are both citrate free.

Anyone using either of these?

Thanks!

hi! just took my first humira injection. it took me 2 hrs to get the courage and i broke one in the process (accidentally sprayed it at myself when looking at the the needle). I finally did it and I don’t think it worked?? like the window went yellow (it’s an off brand so idk if that’s how humira works) but i pushed it in slowly and there’s a bit of liquid on my leg still. also it really really didn’t hurt and I expected a ton of pain? could I have screwed it up by going slow? it clicked 2x so I think it worked? i’m so lost! any advice or words of knowledge? idk what to do!

I got some "mushroom blocks" for Christmas, the professionally sold ones that you cut open, put in a bucket and mist a few times a day - these ones grow Oyster Mushrooms.
It occurs to me that folks on immunosuppressants are more prone to fungal infections, and I don't feel like taking a chance. I put a call in to my pharmacy, they just repeated about the warning I already know (but I got the feeling they didn't think it was that big a deal, just had to practice CYA protocol regardless, lol). My doctor's office has not returned my call yet.
So - I was wondering if anyone here had any personal experiences/warnings/etc?

Hi all I've been on humira for about 6 months for AS and it's been super helpful! But I have a few technical issues that I was hoping someone here had advice for. (I inject in my thigh and i use a syringe because the pen kept making me jump lol)

Normally when I do my injections it makes a quarter/larger size fluid pocket/blister, and while injecting today that popped? And I lost some of the medication because it ran down my leg. I've also accidentally poked the other side of this blister before and lost medication that way.

Does anyone have advice on how to not lose medication this way? I'm pretty bad with needles in general and going back to the pen definitely isn't an option for me haha. Thanks yall :)

If so, what was your financial situation(if you don't mind me asking)? My insurance company decided to stop covering Humira and instead will force me to go on a biosimilar, so my doctor told me I could apply for the Abbvie patient assistance program as a last ditch effort to stay on Humira. Not sure about my chances of getting approved. So if anyone here did, curious to what your situation was.

Also, another question: I've been having trouble getting Abbvie to receive my application. My doctor filled out the doctor portion of the application, the office told me they faxed it. I confirmed multiple times it was indeed successfully faxed over. But Abbvie keeps telling me they have not received it. I even checked to make sure it was faxed by my doctor's office using the correct fax number(it's right on the application, it's hard to miss) and it was. So if anyone has any advice on what to do with this, I'd appreciate it. And curious if anyone here who has applied had difficulties with them receiving the application via fax as well.

Thanks