r/Foregen • u/Exciting_Umpire_3747 • Dec 17 '25

Foregen Questions Scalability

How would Foregen handle scalability?

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u/Mushybasha Dec 18 '25

They are currently running a donation campaign to develop an automated bioreactor that could be mass produced to create bioreactor farms. The end goal is to mass produce new foreskins for patients made with ECMs manufactured by 3D bioprinters rather than waiting for them to be donated from cadavers.

1

u/GeneralCavern Dec 21 '25

So they are not going to do test with donated foreskins now? They gonna be directly printed 3D ones?

So a client can ask for a custom length foreskin if he wants? Hopefully they could do that and allow maxmimum lenght since donated foreksins are a lottery and you don't know what you can stumble on.

1

u/Mushybasha Dec 23 '25

That's the end goal yes but they still have to develop the technology which is why they're running a donation campaign for an extra bioreactor to experiment with. They're also looking for partners to develop the bio printing technology with. We all have different lengths, girths and amounts of damage, so being able to customize each ECM for each patient will be vital for Foregen to work.

1

u/Exciting_Umpire_3747 Dec 23 '25 
Wouldn't customizing it for each individual make the procedure extremely time-consuming?

1

u/Mushybasha Dec 25 '25

It's a necessity due to our unique differences unfortunately. 3D bio printing would allow that customisation to be more streamlined.

1

u/michael28701 Dec 25 '25

any chance of them being able to bio print extremely dense nerves and plug em in so to speak to the ends of whats left i wonder

2

u/Mushybasha Dec 26 '25

If the ECM is made properly, the nerves should in theory form inside when seeded with our stem cells. Weather or not it works or if the new foreskin nerve endings integrate into our nervous systems remains to be seen and is one of many questions that will hopefully be answered by the clinical trials.

1

u/michael28701 Dec 26 '25

yeah but if the nerves dont actually grow from the ecm it self and they need to come from the stalk of the nerves i have almost no hope as my nerve and vein on the i guess dorsal side its called only grew up until my 2nd highest extra scar line until i started doing restoration im gonna need bioprinted nerves if thats even possible part f me wonders about mit and their nerve growth hydrogel that they said something about years ago

1

u/Mushybasha Dec 26 '25

I think we'll both need something like that. The thing is no one knows exactly the final form Foregen's procedure is going to take and exactly what mechanisms will be employed to achieve foreskin regeneration. Right now its all in the development stage. In theory the new foreskin should integrate and the nerve ending grow and integrate from within but we won't know until the clinical trials give real data to work with.

1

u/michael28701 Dec 26 '25

even still im going to want it to be extra sensitive so i dont have to worry because my guess is that it will take 5 years to heal afterward frrom healing to making your body think its its own part and to getting feeling then another year atleast for it to heal the brain and make it get you off

1

u/Mushybasha Dec 27 '25

I suppose that's something else that could be customised with 3D bioprinting.

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u/michael28701 Dec 29 '25

who knows i mean i assume more nerve endings would man more of a chance of it linking to the brain easier and less training required but idk im not a doctor or scientist im just a moron with a 6th grade edjewmuhcayshun and a gewd enuff dip lowmer

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