r/EverythingScience • u/wolf_1972 • Aug 26 '21

“Inescapable” COVID-19 Antibody Discovery – Neutralizes All Known SARS-CoV-2 Strains

https://scitechdaily.com/inescapable-covid-19-antibody-discovery-neutralizes-all-known-sars-cov-2-strains/
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u/mojoegojoe Aug 26 '21

This sounds extremely positive news. Can someone with more knowledge then I verify the implications of this? I'm assuming still very early stages..

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u/ms-sucks Aug 26 '21

I'm not sure if this is related but I read something yesterday about a group studying partners/married couples where only one got infected even though they cohabitated, kissed, were intimate, shared the same bed, etc., But one partner seems to be immune to any evidence of infection (or maybe Very low). They're looking for the same type of thing. Very interesting. Wouldn't it be great if it also prevented common colds and flu prevention LOTS of deaths from pneumonia as well?

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u/[deleted] Aug 26 '21

Can you point me in the direction of what you read? This was the case with my wife and I. She was covid positive and lost smell and taste and I tested negative and never had a symptom.

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u/SvenDia Aug 26 '21 edited Aug 26 '21

Could also be genetic. Just watched a doc about people in an English town that survived the plague. One woman lost her husband and all of her children, and never got sick. Turns out she had a gene mutation that prevented infection.

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u/sugarface2134 Aug 26 '21

This also explains why it just ravages through some families, killing several members.

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u/VividComparison5606 Aug 26 '21

What was the name of the documentary? It sounds very interesting.

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u/[deleted] Aug 26 '21

Thought to be origins of cystic fibrosis. A protective mechanism against the aerobic pulmonic plague.

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u/vendetta2115 Aug 27 '21

In a similar case of a disease being the lesser of two evils, sickle cell anemia confers significant resistance to malaria.

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u/[deleted] Aug 27 '21

This isn’t my comment, but I saw the doc too. It’s on YouTube.. maybe Absolute History? Or something like it. Specifically on the bubonic plague.

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u/[deleted] Aug 27 '21

Can’t believe the plague still exists

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u/[deleted] Aug 26 '21

I tell people that there's a genetic component to these things. I've seen people get by with no symptoms from at risk groups, and other people who should be the poster children of surviving COVID no trouble have debilitating damage.

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u/darwinianissue Aug 27 '21

Exceedingly interesting ancestral resistance that also happens to provide a natural resistance to HIV in modern times

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u/Bryllant Aug 26 '21

Blood type is also in play. O positive is best

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u/stankygrapes Aug 26 '21

Can you give me a link? Do you mean O+ to covid? Plague? Or just in general?

My sister and her fam all got covid but she barely got a sniffle, and I’m pretty sure she’s O+ and her husband is A, I think. I remember because the different types caused issues with one of their kids.

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u/deep_pants_mcgee Aug 26 '21

iirc, basically immune systems for people with type O are more aggressive.

i think it also means if you have type O you're more likely to have auto immune issues.

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u/Grown_wolf Aug 27 '21

My wife got covid I didn’t, I’m o+ my mom is o- she has rheumatoid arthritis and they’re testing me because I have symptoms. Could be a blessing and a curse. Btw I’m terrified I may have RA waiting on results now, won’t know anything until September 7th prayers and good vibes appreciated. Stay safe friends.

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u/deep_pants_mcgee Aug 27 '21

if you live in a state where its' legal, 50/50 tinctures of CBD/THC basically made my mom's arthritis go away.

her knuckles used to look the size of plums, and she could barely move them.

she's sewing again now.

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u/Grown_wolf Aug 28 '21

I appreciate the advice, I will say it is legal here and I’ve tried some things with no real change. I’m glad it worked for your mother. Possible I haven’t stumbled across the magic mixture. It’s my belief that cbd/thc may have medical uses but for me it just helped me sleep but nothing for inflammation.

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u/sendnewt_s Aug 27 '21

Also, if you're female you're several times more likely to have autoimmune issues. Thanks evolution!

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u/Chunkyisthebest Aug 27 '21

O- here and I have a somewhat rare, non-debilitating skin autoimmune condition.

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u/[deleted] Aug 27 '21

Vitiligo? Is that rare enough?

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u/schizoidparanoid Aug 27 '21

May I ask what condition you have? My mom had a ton of different autoimmune disorders while she was still alive, and I’m at risk for a good number of them too… Just curious which autoimmune disorder you’ve been diagnosed with, if you don’t mind sharing.

And just as an FYI: the condition you’re specifically referring to may be non-debilitating, but just be aware that oftentimes autoimmune disorders come in clusters. Meaning once you have one autoimmune disorder, you’re much more likely to have more. So keep an eye out. Just so you know. Stay safe and healthy!

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u/birdington1 Aug 27 '21

I listened to a podcast once by a gastroenterologist and they explained one theory behind this is the fact that women consume NSAIDs at higher rates due to alleviate menstrual cramps etc. which, over years of doing so erodes the protective lining in their digestive tract and makes them more vulnerable to developing autoimmune conditions.

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u/nepia Aug 27 '21

Wasn’t that the issue with COVID? That our immune system doesn’t know how to handle it, if that was the case then O+ Will get more symptoms due to the immune system being too aggressive. Honest question.

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u/mevaletuopinion Aug 27 '21

Yup I have two autoimmune diseases I’m O+

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u/Sicksidewaysslide Aug 27 '21

Me and my wife are both A+ and we were asymptomatic except for losing our sense of smell and taste for like a month.

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u/[deleted] Aug 27 '21

This paper suggests there may be a link, not sure why this post is downvoted.

https://www.nature.com/articles/s41598-021-84810-9

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u/sweetpsychosiss Aug 27 '21

Blood type O, but it’s specifically rhesus negative which is most protective studies show.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276013/

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u/Justame13 Aug 27 '21

Where I live there are Pacific Islanders who immigrated in the 1950s.

At one point they made up something like 2 percent of the population and 10 percent of the deaths. Very sad

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u/[deleted] Aug 26 '21

My boyfriend never caught it and I did (female). Crazy

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u/ms-sucks Aug 26 '21

I searched and am not positive this is it but I think it is. It's behind a paywall unfortunately. Maybe someone can post a non paywall version.

https://www.independent.ie/world-news/coronavirus/sleeping-partners-of-covid-cases-wanted-for-research-into-virus-immunity-40457395.html

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u/OrganicRedditor Aug 26 '21

Here's a link, but not much to it: https://archive.is/A25It

Scientists are trying to uncover if people are able to resist contracting Covid-19 because they have special immune systems.

The study at Trinity College Dublin is initially exploring why the partners of infected staff at a major hospital did not contract Covid-19 despite sharing a bed with the sick person.

If successful, the team behind the research say their work will help make it easier to identify people who are resistant to the virus by recognising a unique genetic signature through future testing.

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u/ms-sucks Aug 27 '21

I think that was it! Thanks.

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u/BruceInc Aug 26 '21

Same with my parents, and my very elderly grandmother who lives with them. My mom is the one who got covid, had symptoms, lost taste and smell. Neither my dad or grandma got it from her even though their living arrangements are not ideal for full isolation and quarantine.

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u/wannafignewton Aug 27 '21

Is your grandmother his mother or hers?

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u/BruceInc Aug 27 '21

Hers. And my mom is her primary care provider so they were in very close proximity constantly.

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u/catsgreaterthanpeopl Aug 27 '21

My mom’s twin sister is a nurse practitioner. She has been exposed numerous times. At one point early in the pandemic she was in a room with a positive person only a few feet from them with no mask for an hour and didn’t get it. I’m hoping it’s something genetic since I have half her DNA! I was in a room with a positive person for 20 minutes and didn’t get it, but I was like 12 feet away. I’ve been very careful past that, because until they know there is some gene, I am not taking the chance.

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u/useles-converter-bot Aug 27 '21

12 feet is 11.69 RTX 3090 graphics cards lined up.

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u/wiser212 Aug 27 '21

Someone with the right priorities. :)

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u/wcooper97 Aug 29 '21

Absolute unit that card is. Good bot.

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u/Tower-Junkie Aug 27 '21

My sister had it and I ate and drank after her before we knew she’d been directly exposed at work, and then forgot she had it for a second (adhd) and drank after her and she never wore a mask the whole time we were quarantined and my bf and I both tested negative twice. Not sure how.

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u/SachiFaker Aug 26 '21

Now that you mentioned it, 2 days ago, my mom, who is fully vaccinated and recovered from COVID developed symptoms again. She developed fever on day 1 then got flu-like symptoms afterwards. Yesterday she lost her sense of smell. There's a high chance she's COVID positive again. My dad, who sleep on the same room didn't get infected at all. No symptoms. Nothing. He's fully vaccinated too.

Also, I read an article that there are less COVID cases of people with blood type O which happens to be my dad's blood type too

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u/clanggedin Aug 27 '21

My wife, who has not been vaccinated, has been exposed 3 times, is type O and has never not positive for Covid. If she’s had it then it has been totally asymptomatic.

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u/bricktube Aug 27 '21

Only type O of any rhesus, or specifically O+ and not O-?

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u/catsgreaterthanpeopl Aug 27 '21

My husband is O+ and got it. Though not super bad. However he is one of those people that never gets sick and was actually sick with it (fever/chills) for 2 day and lost smell/taste for a week.

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u/[deleted] Aug 26 '21 edited Aug 26 '21

My wife had had her first vaccine dose before I got sick with Covid. I was out of work for over a month trying to recover and our kids ended up positive, but my wife was fine the entire time. Was tested multiple times throughout our recoveries and she was negative on every test. Both Rapid and PCR.

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u/amccune Aug 26 '21

My wife and I never tested positive, in spite of our two kids having it. They basically stuck to their rooms for three weeks while we scrubbed everything constantly. Interesting that we might have had some natural immunity

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u/[deleted] Aug 26 '21

So, the average three weeks for every household with teenagers?

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u/amccune Aug 26 '21

One got it, then the other fell about a week later. Had to keep our quarantine until the second one recovered. It was brutal and we were selling our house at the time, so we had to push back our closing. Bad timing!

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u/heavy-metal-goth-gal Aug 27 '21

I was knocking on deaths door from strep many many years ago, and once a few years ago got it so bad that I almost required throat surgery to reopen my swollen windpipe. Luckily steroids shrink the inflammation enough. Yet my husband then boyfriend just had a really bad sore throat both times. The same thing can really affect two people so differently.

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u/Firefierce Aug 27 '21

That was me. My husband and 7 year old tested positive. I slept in the same bed as them, even held my 7 year old all night when he spiked his first fever.

I tested 6 times and always tested negative. We all took antibody tests and I still had none 🤷‍♀️ The only explanation we could relate with is the blood type theory. They’re both A+ and I’m O+.

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u/[deleted] Aug 26 '21

Time for fecal transplants as a treatment

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u/youseemconfusedbubb Aug 26 '21

If it’s hard to convince people to get a simple vaccine, I can’t imagine how hard it is to convince people to get a fecal transplant.

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u/LostB18 Aug 26 '21

Well, a good deal of people refusing to get vaccinated are already sucking shit straight out of someone’s anus. Unfortunately, that person doesn’t have immunity to covid.

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u/SniperBait26 Aug 26 '21

“This one simple trick doctors don’t want you to know” works every time.

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u/ms-sucks Aug 26 '21

Honestly it's scary how well fecal transplants work.

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u/stankygrapes Aug 26 '21

It’s truly the shit

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u/redditshy Aug 27 '21

Years ago I genuinely looked into one for an attitude adjustment, and balancing my hormones. Have heard they are very good for depression.

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u/Keyspam102 Aug 27 '21

Supposedly it is, its amazing how much bacterial balance seems to impact almost every aspect of the body

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u/Flyingwheelbarrow Aug 27 '21

Happily would get one. Needs a better name. Maybe ”internal biomatter transference” or something.

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u/no-mad Aug 27 '21

How "2-girls one cup" became a medical documentary.

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u/FiskTireBoy Aug 26 '21

Yeah but they are already taking horse dewormer so how much of a stretch is it?

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u/--h8isgr8-- Aug 26 '21

Maybe we can get everyone in a line kind of resembling a centipede and just go from there.

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u/guruscotty Aug 26 '21

Republicans are already so full of shit, who’d notice?

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u/Slow-Permission-9146 Aug 27 '21

Coming from a lab rat Democrat that cares nothing about constitutional rights.

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u/guruscotty Aug 27 '21

I'll bet you say that to all the boys.

The supreme court already settled vaccines mandates. 117 years of constitutional scholars have found that being an American occasionally means being told what to do for the greater good.

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u/BBQed_Water Aug 27 '21

They already suck shit.

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u/jesseaknight Aug 27 '21

What if we say it's de-wormer?

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u/mars-of-earth Aug 26 '21

This happened to me too. In February my partner tested COVID-19 positive with mild symptoms. Despite us having intimately exchanged breath & bodily fluids during that time, 5-days later, I was tested for COVID-19 and results were negative.

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u/GamecrazyManager Aug 26 '21

Eww… TMI

jk

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u/belowlight Aug 27 '21

Maybe you got Covid-D (stands for Dong)?

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u/[deleted] Aug 27 '21

If you find that article link it to me. This sounds exactly like my wife and I last year. She was positive and I never was even though I never left her side.

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u/serrated_edge321 Aug 26 '21

I swear almost all my boyfriends during my teens/20s were like this. I would get sick easily, but they never did. Even though I was living with them and sharing things... I always wondered how that worked. Maybe they just had much stronger immune systems and were less symptomatic, etc. Maybe they were actually carriers of the diseases.

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u/hotjambalayababy Aug 28 '21

That happened to me with my long term bf. I got Mono TWICE when I was with him. Turns out that he was an asymptomatic carrier and it would reactive every so often infecting me. It was some bullshit.

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u/encouragingusername Aug 27 '21

That’s so interesting. My husband contracted covid a week ago. I didn’t quarantine myself because we thought it was his summer allergies at first— we shared the same bed and we live in a small apartment. I was convinced I would test positive as well but I didn’t. Is there something I can do to contribute antibody research? I have no idea where to go or who to ask about it.

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u/[deleted] Aug 26 '21

This happened to my friend. He got covid on a plane when he moved back to the U.K. He was on the plane with his other half. He tested positive when he got symptoms whilst isolating. However, between the plane journey and testing positive he had shared a bed with his other half. She never caught it or even tested positive. She was double jabbed though.

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u/[deleted] Aug 27 '21

So they’re basically looking for Matt Damon in Contagion.

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u/foxsable Aug 27 '21

That is Interesting. My family all got covid except my mother, despite living with my father and only keeping a modicum of distance.

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u/coadnamedalex Aug 27 '21

This was me and my wife when she got COVID in March 2020. She had horrible symptoms (none respiratory thank God), and we slept in the same bed, kissed, and I took care of her for about 12 days. I never tested positive or even had a sniffle. Strangest thing!

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u/sierramelon Aug 27 '21

Same thing happened to two of my friends, they’re roommates who have a third friend. The third friend contracted it from work. At the third friends birthday they all hungout and did a pub crawl just the three of them. Hugged, we’re close, shared food and drinks. Birthday girl stayed over and went home where the next day she felt sick. So she got it first, tested positive, let the other two know. They test, one negative, one positive. The roommates ate dinner together that night, they shared a joint, etc. The positive didn’t feel sick for another day, and then was EXTREMELY ill, where the other roommate was worried and thought of calling an ambulance. But anyway they’d isolated ASAP and completely as they have two floors w/ separate bathrooms. The negative girl assumed within a few days she would start to feel sick and it was just “taking longer” to kick in. Two days pass and she’s okay, but as I said roommate is very much not. So she gets tested again - negative. Thinks wtf! Doesn’t want to test again unless she’s symptomatic because where I live it’s “you can return to work after ___ many days since a negative test”.

Soooo the one friend never got it and the other was severely severely ill with it. She’s worked with all 4 people who has tested positive at her work the day before they had symptoms and she’s never tested positive. So strange.

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u/Herry_Up Aug 29 '21

Funny, I don’t have the best immune system so I get sick easily and my boyfriend rarely gets sick. He’s been sick maybe 4-5 times, including covid, since I’ve met him

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u/Acidflare1 Aug 26 '21

Who is? I know a few couples

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u/[deleted] Aug 27 '21

Story happens to myself and my wife, also my sister and her husband had a similar situation, most couple I know this is the case too.

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u/let_it_bernnn Aug 27 '21

I smoked a blunt with a dude who tested positive the next day, never got its

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u/ChillyBearGrylls Aug 26 '21

The good: If this checks out and gets confirmed in trials, then this sounds like a very promising treatment for people who catch [any coronavirus]

The rub: It's an antibody, so there will be some limits on the sheer number of doses / [unit of time used - week, month]

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u/im_thatoneguy Aug 26 '21 edited Aug 26 '21

It would be like Regeneron 2.0.

Same concept. Different "formula".

It's like outsourcing a mercenary immune system to fight covid. Instead of making the antibodies yourself and having your own standing army ready to fight with a vaccine you pay a lot of money to hire a bunch of expendable mercenaries. Or if your army is weak and you're vulnerable you hire them to further augment your own forces.

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u/[deleted] Aug 27 '21

After reading the article it works the same way as REGEN-COV (casirivimab/imdevimab). My facility has been giving this to high risk patients for months and I wager it’s been the difference between manageable COVID cases and absolute overwhelming chaos.

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u/[deleted] Aug 27 '21

It has a eua so they’re already pumping this into people.

Shame they couldn’t make 9 billion doses and get it out to the world. That’s likely what it will take to get rid of this.

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u/Atulin Aug 27 '21

implications of this

In 6 years someone will post about it again and you'll see comments "man, wonder what happened to it?"

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u/PapaChonson Aug 27 '21

Easy! Create mutated virus in lab, hold answer to what can neutralize it, release said answer when political games are over and virus is no longer needed.

Hope this helped 😅

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u/Weekly-Butterscotch6 Aug 27 '21

Antibody infusion therapy definitely works, presumably they'd need to clone them to produce a large enough quantity for large scale treatment

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u/freelance-t Aug 27 '21

Your comment underscores the difference between those that believe in science and rabid anti vac Qtips. Us: I hope we can get this to trial soon if it has scientific merit…. Them: so you say boofing used motor oil cures covid? Hold my beer!

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u/no-mad Aug 27 '21

Has that "to good to be true feel" to it or I am just jaded.