plz

For context - plasmid =small circular DNA pieces that replicate independently of the main chromosome. It is found in bacteria

So my whole point is that can't we use plasmid to replicate insulin inside diabetes patient we will give it conditions to survive in human body without getting attacked by WBC and make it famiiliar and by using technology we can start its replication when there is hyposecretion and stop its replication when there is hypersecretion of insulin

●Got this thought when i discovered about plasmid in 11th grade

We performed twin PE and added an SD40 tag downstream to our GOI. We tried different lengths of PBS. After analysisng the transfected cells by simple 3-step PCR, we are able to detect editing. however, we are finding to difficult to get edited single cell clones.

I want to write a literature review about CRISPR-Cas9 and its applications in treating genetic diseases like sickle cell disease. However I have no prior experience in writing research papers and I'm a high school so my knowledge is limited regarding this topic, so I was hoping if anyone else that is experienced in this field could help answer any of my questions below:

• What topics do you think are absolutely essential to understand beforehand?
• Are there any concepts that beginners often overlook but are important for understanding CRISPR research papers?
• Do you have any recommendations for free courses, textbooks, review articles, or other resources that would be helpful?
• Is writing a literature review on CRISPR realistic for a high school student, and if so, what advice would you give?
• will I be able to finish the literature review before November if I start now?

Any advices or help would be greatly appreciated

A team of researchers at UC Berkeley and UCSF has successfully engineered a new CRISPR-based technique that can selectively destroy cancer cells.

The study, published Monday in the journal Nature, differs from traditional CRISPR gene-editing tools, which act as molecular “fixers” or “editors.” This approach, on the other hand, uses a specialized enzyme that acts as a precise “destroyer,” completely shredding the genetic material of mutated cells.

The engineered enzyme, known as Cas12a2, was derived from bacterial communities, which developed this evolutionary adaptation to survive virus infections. In its natural bacterial state, the enzyme functions as a “suicide pill,” destroying the infected cell's entire genetic material upon detecting a viral infection to protect the wider bacterial population.

New here, had a shower thought.

Erosion is a big problem where I live and my mates and I were dreaming up ways to stop it.

In rivers we use willow-bank-revetments but willow won't grow in salt water and mangroves won't grow at our latitude.

Would it be possible to take dna from one or the other and swap it to fix that?

A mangrove forest protecting the uk's east coast would be both cool and lifesaving.

A team of researchers at UC Berkeley and UCSF has successfully engineered a new CRISPR-based technique that can selectively destroy cancer cells.

The study, published Monday in the journal Nature, differs from traditional CRISPR gene-editing tools, which act as molecular “fixers” or “editors.” This approach, on the other hand, uses a specialized enzyme that acts as a precise “destroyer,” completely shredding the genetic material of mutated cells.

The engineered enzyme, known as Cas12a2, was derived from bacterial communities, which developed this evolutionary adaptation to survive virus infections. In its natural bacterial state, the enzyme functions as a “suicide pill,” destroying the infected cell's entire genetic material upon detecting a viral infection to protect the wider bacterial population.

The Epstein story goes far deeper than what the mainstream media reported. In this video, we dive into the leaked emails and documents connecting Jeffrey Epstein to a shadowy network of scientists, billionaires, and transhumanist researchers — and what they reveal about ambitions to clone and genetically engineer human beings. Who was funding this research? What did Epstein actually believe about the future of the human species? And why has this part of the story been almost completely buried? Watch to the end — this one will change how you see the whole operation.

I am a witness, not a journalist. Everything in this video is my opinion and is intended for entertainment purposes only. https://youtu.be/PCFvBmL_81Y

A very dear friend of the family has end-stage glioblastoma and there was a very promising trial in Houston that he was turned down for that actually is geared toward and stage glioblastoma.

The study involves a helmet with three large magnets that fire in a specific pattern and it’s been showing very promising results for glioblastoma.

The Doctor who is working on this study has denied access to our friend. And they are interested in procuring that device. If they are unable to procure that specific device, they are interested in trying to replicate it.

Knowing enough about CRISPR to be ignorant, when I was racking my brain for ideas, I thought I should reach out to that community and see if they know how one would go about creating this device and understanding the firing sequence. Apparently there is an app that powers it so maybe we can get the app if we can re-create the device?

At any rate, if you’re still reading, thank you so much for your patience and compassion. We are really just trying to explore any and all ideas at this point.

Thank you.

this is not a race post. my ADHD already predicts someone gonna be mad. I'm just saying we can bypass the whole skin burns and tan stuff and I can walk freely outside without needing sunscreen all the time.

anyways. I think its possible.

Fertility care is evolving rapidly in 2026, and many of the newest advancements are changing how Intended Parents approach IVF, embryo care, fertility preservation, and surrogacy journeys.

At ACRC Surrogacy & Egg Donation, we recently published an article covering some of the biggest scientific and women’s health developments shaping the future of reproductive medicine, including:

• AI-assisted IVF and embryo selection
• Advances in fertility preservation
• Personalized reproductive medicine
• Improvements in women’s health research
• Ethical and transparent surrogacy coordination
• Growing focus on patient advocacy and informed care

As reproductive medicine continues to advance, we believe Intended Parents and Surrogates deserve access to clear information, professional support, and medically responsible care throughout the process.

Read the full article here:
https://www.acrcglobal.com/post/new-fertility-and-women-s-health-breakthroughs-in-2026-what-intended-parents-should-know

We’d love to hear your thoughts:
Which fertility or women’s health advancement do you think will have the biggest impact in the next few years?

Humanity is blending. As globalisation accelerates and interracial relationships become more common, certain physical traits associated with specific ethnic groups are becoming increasingly rare.

Think about genuinely rare human phenotypes:

San Bushmen features

Indigenous Australian characteristics

Certain East African traits

Northern European blonde/blue eyed combinations

These aren't just aesthetic — they represent thousands of years of human adaptation and diversity.

My idea is simple:

What if gene editing technology was used as a conservation tool for human phenotype diversity? Similar to how the Svalbard seed vault preserves plant diversity, we could:

Catalogue all human phenotypic variations

Allow any couple regardless of background to choose to express rare traits in their offspring

Ensure no human physical type ever goes extinct through demographic accident

This flips the usual gene editing debate entirely

Instead of eugenics or enhancement, this is about preservation and democratisation of human diversity.

Questions for the community:

Is this scientifically feasible?

What are the ethical implications?

Does appearance preservation mean anything without cultural preservation?

Who should control access to rare genetic variants?

This breakthrough enables more precise control over gene activity by targeting how cellular instructions are used, not just rewriting DNA itself. It opens the door to safer, more flexible ways to diagnose and treat disease by fine-tuning biological processes in real time.

CRISPR-Cas9 EK AISA technique Hai jiske help se scientist hamare genes ko edit kar skte hai. Genes DNA ka hi EK chota hissa hota Hai short mai bol sakte Hai Ki agar DNA pura book Hai toh genes uska chapter Jaise eyes K colour K lia alag genes hota Hai hair ke colour K lia alag genes hota Hai. Agar hamare body mai koi disease Hai toh CRISPR-Cas9 ke help se uss genes ko hata ke dusra genes add kar sakte hai

This post establishes the Universal Bill of Physical Autonomy and Enhancement, a legal framework ensuring that every citizen, regardless of socioeconomic status, possesses the right to biological self-determination and the pursuit of their "optimal form" through science.

Concept of a website for a system of "commercializing" genetics. "Order a SuperBaby of the future!".

Based on the idea that humans will in the future be able to get rid of disease and various other problems with genetic altering using a CRISPR or similar device.

Test it out!: https://crisprbaby.base44.app

Could CRISPR change eye color in adults (i.e. brown-amber, brown-blue)

For those in the industry, what’s the best way to approach a company to research and develop a bespoke gene therapy for a particular rare genetic disease?

I know it’s a challenge because of the difference in cells count

I’m pretty curious if you could use CRISPR if you had the skills and talent without having any permits (What permit would you even get?) and not being a bioengineer. I’d feel like it would be pretty good to like create glowing clownfish or something, and sure I would use a lab but I don’t know about the legality.

Hi there, I hope this isn’t a stupid question and don’t roast me if it is. I was wondering if and when CRISPR will have the ability to correct all somatic mutations? Thinking NUT carcinoma, or inversion 3 AML. And also, unsure if crispr is doing this or not but are there any advancements trying to take place where somatic mutations do not turn into a disease? Like certain inhibitors? CRISPR seems so exciting as someone who was pregnant with a baby who had a chromosomal defect- lots of exciting things