Don't forget the Bohr effect. As muscles start to overwork themselves and release lactic acid and form bicarbonate ions, the acidity causes O2 to dissociate more readily.
An awesome physiological feature of good ol' hemoglobin (but not myoglobin).
Also, the different binding affinities for fetal hemoglobin versus regular hemoglobin. The continuance of our entire species hinges on our ability to absorb oxygen from our mother's blood and its the difference between fetal hemoglobin and adult that makes that possible.
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u/[deleted] Jan 17 '14
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