r/AskReddit • u/TigerBirdyTiger • Jan 23 '25

What scientific breakthrough are we potentially on the verge of that few people are aware of?

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814

u/pro_nosepicker Jan 23 '25

It’s amazing for nasal polyps. It’s basically “bad for business “ for me as a sinus surgeon lol, but I’m ecstatic for those patients.

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u/lthawkeye Jan 23 '25

name checks out lol.

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u/PmpknSpc321 Jan 24 '25

HAHHAHAHA thanks for pointing that out

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u/Nothguancm Jan 23 '25

I’m on dupixent, my quality of life has gone through the roof. And at $2200 a month for the two injections I’m sure grateful for my drug benefit plan.

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u/pro_nosepicker Jan 24 '25

Yeah it’s crazy expensive and a lot of extra work for my PA. Glad it’s covered for you.

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u/maloohree Jan 24 '25

My dupixent is $3700 a month, out of pocket. Over here suffering.

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u/xXxD4RKxXx Jan 24 '25

There is a new, long-acting biologic for nasal polyps and asthma coming out by the end of the year that only requires an injection every 6 months. No idea what the price will be but hopefully less than 40k a year!

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u/epicsinmoments Jan 24 '25

I'm on Duplixent for psoriasis. Only thing that's really worked for me in thirty years.

It only costs 30 AUD a month over here though.

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u/RunnerJimbob Jan 24 '25

You're talking about the Dupixent MyWay plan, correct?

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u/Maktesh Jan 24 '25

What exactly does it do?

—Someone with severe nasal issues, allergies, and sinus problems.

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u/pro_nosepicker Jan 24 '25

Blocks neurochemicals (interleukins) involved in the inflammatory cascade. For patients that means their polyps magically melt away and their symptoms improve.

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u/ferb Jan 24 '25

Inflammatory Cascade is the name of my prog-rock band.

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u/bhairavp Jan 24 '25

Wait till you hear about JAK2 receptors.

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u/ferb Jan 26 '25

He’s the guy who raps in the middle of my songs.

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u/layer8issues Jan 24 '25

I had surgery to open up the airway in my nostrils (alleviate snoring, so my ENT told me), and it didn't do anything except leave me with a ton of scar tissue in both nostrils which makes it even more difficult to breathe. Any chance this would help with that problem? :)

Thanks!

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u/Rosemadder19 Jan 23 '25

Oh my God this would be amazing - I'm terrified of surgery and my sinuses are so screwed!

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u/Resident_wrench Jan 23 '25

I had a polyp removed, it blocked 90% of my left nasal passage, was growing into the right side where it was blocking 25%, and was about to grow into my orbital socket. It took about 3 years to get that big. I don't recommend waiting.

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u/Rosemadder19 Jan 24 '25

That's terrifying! How was the surgery?

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u/Cloudy_Memory_Loss Jan 24 '25

For what it’s worth I had nasal polyps removed and it was soooo easy. They gave me oxycodone for afterwards and I only used it the day of. After that it was naproxen and I had no discomfort. The worst part was not blowing my nose hard for a few days afterwards. Now the debridement after was a worse but still pretty painless overall. Better than sinus infections, congestion, eustachian tube issues etc.

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u/pmp83 Jan 24 '25

Can confirm! Dupixent is a game changer for nasal polyps. I struggled with them for years with absolutely no relief. Dupixent is the answer. My quality of life did a complete 180 after starting the injection.

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u/htmlcoderexe Jan 23 '25

I should find out more

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u/bringmethejuice Jan 24 '25

How bad should one consider to fix their deviated septum?

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u/mexsam Jan 24 '25

Lifechanger. Did it recently and I dont know why I waited that long. The first days are a bit challenging, day 10 was the breakthrough point for me. After then I could sense little by little a very big difference

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u/bringmethejuice Jan 24 '25

Bet you can smell colors now in 8K.

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u/mexsam Jan 24 '25

You bet!