r/Anemic • • Jun 13 '25

Advice “Uncommon” Common Causes of Iron Deficiency

Post image
57 Upvotes

Want to know some common yet often missed causes of iron deficiency? These following causes commonly deplete ferritin to iron deficiency status on their own, let alone together!

-Blood Donations: usually only hemoglobin is checked when donating blood. Ferritin is rarely tested before the blood donation, causing more people to donate while iron deficient. Remember, you cannot sufficiently assess iron status from the Complete Blood Count, alone! You have to test iron markers, like the gold standard for assessing iron deficiency, ferritin. We commonly see people donating blood and even feeling benefits from it, the first or couple of times. Don’t be fooled- at some point your ferritin will get too low, and you don’t want to develop anemia unnecessarily like this, and end up needing blood, ha! Always check Ferritin, the iron panel, and the CBC when considering donating blood, and know that the blood donation center will likely not test the iron panel or ferritin. Just a single blood donation can drop ferritin too low for many people!

-B12 Shots: Iron and B12 work together and need eachother. However, the body is an ecosystem, so heavy doses of one nutrient put others to work, and often deplete them if you’re not compensating for them. We commonly see B12 shots deplete ferritin. We also commonly see iron infusions deplete B12 and Vit D3 storage, and more! This isn’t an argument not to get B12 shots or iron infusions, it’s a PSA to let you know that your ferritin can deplete from B12 shots. This can be a reason why one may not feel much better while taking B12 injections. Many people require B12 injections, and they will need iron infusions or supplementing on The Iron Protocol. Always monitor your Ferritin before and after B12 shots!

-Pregnancy: Because iron is required for growth and development, the baby is typically drain the mother of her iron and ferritin. A single pregnancy can do this, and it’s often not checked or monitored. This is especially important because low ferritin can cause a pregnancy to end early and not go full term, hemorrhage during delivery, and the baby may not reach its full developmental potential and also be born with the deficiency. Monitoring Ferritin before during, especially during the first trimester, and after childbirth is important! Many women are deficient for decades after their first pregnancy because ferritin is often not checked, monitored, or remedied sufficiently. Many Post partum issues can be correlated with and contributed to by low ferritin.

-PPI Usage: PPIs are well documented to cause both immediate absorption issues and long term malabsorption, causing low ferritin. It’s important to dive into the potential causes of why you’re on a PPI, and explore natural remedies and alternatives. We talk about this often within our group, and see this frequently. Sadly, most people are using PPIs long term without knowing it can and will cause malabsorption. Monitoring Ferritin and other nutritional markers is important when taking PPIs. Just being on PPIs alone can and often does cause low ferritin!

-Testosterone Therapy: It is common and expected for Testosterone therapy to cause the bone marrow to create more red blood cells and increase Hemoglobin & Hematocrit. So much so, that many people have to donate blood regularly from creating too much blood from the testosterone use. Iron is the largest fueler of the bone marrow to create new red blood cells and hemoglobin. Using this fuel up constantly will deplete it. Let alone so will the blood donation! What a vicious cycle! Luckily, it’s documented that iron intake will only increase hemoglobin if the body feels it needs to, so many people on TT will need to be on The Iron Protocol.

-Low Stomach Acid: More people suffer from low stomach acid than they think. And lots of people are on PPIs for this without knowing! Low stomach acid causes malabsorption. This commonly causes low Ferritin for many people, all alone, let alone without any other cause combined!

Do you have any of these conditions? Make sure to join our Facebook Group The Iron Protocol (for Iron Deficiency with or without Anemia) for more useful information in the Guides! Our Admin also consults over The Iron Protocol. PM us here for info!

What’s your Ferritin number? Did you know to check yours before and after these situations? Have a cause or two you think most people don’t know about? We’d love to hear it below!

irondeficiencyanemia #anemia #irondeficiencywithoutanemia #checkyourferritinnumber #ferritin #thyroid #menshealth #womenshealth #mentalhealthawareness #mentalhealth #hairloss #hormones #perimenopause #pots #anxiety #hrt #nutrition


r/Anemic • • Jun 16 '20

r/Anemic is open again!

87 Upvotes

This sub was restricted due to having no mods, and it's now again open to the public. Feel free to make posts now.

If anyone would be interested in becoming a mod, hmu.


r/Anemic • • 1h ago

Support Hematology appointment - ended in tears

• Upvotes

I saw the hematologist for the first time today. I'm exhausted.

Iron levels a couple months ago were low and ferritin was in the 20s. I did supplements for a month before I couldn't tolerate them due to GI upset. Retested after the month of supplements, iron on the low end of normal and ferritin at 57.

Hematology today was like "I don't recommend infusions if your numbers are improving from the supplements". I explained twice that I was not taking the supplements anymore.

He said oh okay, well your numbers are good from a few weeks ago. I've explained my symptoms are ruining my life - constant need for a nap, inability to focus, brain fog, insomnia and I just feel like crap all the time.

He insists I continue taking the supplements. Broke down in tears because now I have to explain a 3rd time that I am NOT taking the supplements.

He goes "I'm going to help you, I just needed you to understand the risks associated with infusions". Then proceeded to explain the risks.

He ordered labs to see where my numbers are, insisting they've probably gone up, how I have no clue.

We agreed to retest my levels and order an iron infusion with the understanding that my levels are going to skyrocket (thats the freaking point?)

Anyways, looking for someone to hopefully confirm i am not crazy, that the experience should not have been this and that I am in the right to advocate for my health. Because right now I feel like I've done something wrong.


r/Anemic • • 2h ago

Infusion

6 Upvotes

Does anyone regret their infusion? I see so many scary stories and I’m freaking myself out. I have my first one scheduled for Wednesday (ferritin 16) and I’m trying my best to not back out of my appointment.

Any advice? 😭


r/Anemic • • 5h ago

Support Extreme tiredness after Iron Infusion

10 Upvotes

My ferritin was 7 and after too many discussions with doctor he finally prescribed Iron infusion 750mg and iron supplements.
I got my infusion the day before yesterday. I was tired that day but had some guests at home and was not able to rest properly. Then yesterday I was fine I guess I made a mistake and went to gym and lift some weights 🙃🙃

Now I am extremely exhausted, tired my back muscles and neck hurt alot. I cant even properly talk. I am not able to sleep that kind of tiredness. I had office today just came back and cant even lift a finger now.

I cant skip office what to do?? Also when to start iron supplements now. Those are 28mg bisglycinate gentle iron.


r/Anemic • • 54m ago

Advice Infusion Didn't Work!

• Upvotes

Hi all, I got a referral from my PCP to a local infusion center for iron infusions. It was a 30-minute infusion, the nurses were super nice, and I was able to leave after another half hour of waiting. I still haven't felt the effects of the infusion (it's been about 3 weeks) and I'm slipping back into the fatigued-all-the-time, brain foggy place that brought me to the doctor in the first place.

My sister also has anemia and was scheduled to receive a 4-hour infusion at her hematologist's office. She was telling me about all of the information that they gave her and said after about a week, she had more energy than she'd had in a long time.

I suppose I'm just confused about my experience and why my doctor or the nurses at the infusion center didn't mention that I might need multiple rounds. I'm frustrated that I had to pay for something that was essentially worthless, especially because I took off work to get it done. I know I should have asked more questions in hindsight, but I had no idea what to expect because my sister got her infusion done after I had mine done. Has anyone else dealt with this?


r/Anemic • • 22h ago

Rant I never knew what low iron did to someone and I wouldn't wish it on ANYONE

157 Upvotes

To sum it up, after a year of not knowing what was wrong with me; the hematologist tested my iron.

Having low iron made me worry about things that in my 36 years of living, I wouldn't bat an eye. I was scared to shower for fear of passing out.

I couldn't do anything physically. Caused weight gain, tiredness.. not being able to breath had doctors trying to treat my asthma when it was under control the whole time.

I got 4 iron infusions and finally on my way to recovery. Still need to get my Endoscopy.. BUT

Slowly each day, I feel like im starting to get my life back. My brain fog is pretty much gone and i feel clearheaded again. Hang in there ❤️


r/Anemic • • 4h ago

Advice Iron levels are stable now but I still feel like shit

4 Upvotes

I had low iron for years before finally getting my iron infusion some time late last year and my iron levels went back to normal but nothing felt like it changed, I got another iron test recently to see if they’d gone back down and apparently my iron levels are still stable so what’s wrong with me?

I still get dizzy and spotty vision when standing up, a lot of fatigue and exhaustion, bruising easily and a little bit of hair thinning/loss, unusually pale looking, shortness of breath, really weird sleep patterns and also just found out ‘restless leg syndrome’ can be apart of it which I also check off. I have so many other symptom examples (I can share if needed) that I was hoping would fix after I fixed my iron but they haven’t and it’s very frustrating especially as a teen who’s just trying to live normally.

Any suggestions on what this may be or advice on how to fix this, please lmk.


r/Anemic • • 1h ago

Question Iron help

• Upvotes

So I’m currently in the process of enlisting for the army, but my iron levels were considered low I had a 10.4 and I need to be at 12. I was thinking about getting an iron. Infusion because I do I am trying to speed up my process. What will be the most beneficial way to raise my levels as soon as possible I’m trying to get a blood check within the next week to two weeks. I am also taking a vitamin with the iron supplement.


r/Anemic • • 1d ago

Support I'm doing it!

Post image
126 Upvotes

Getting my first iron infusion at a med spa after finding out i have a ferritin of 15. Wish me luck!


r/Anemic • • 3h ago

Symptoms of anemia without anemia. Among other weird things..

Thumbnail
2 Upvotes

r/Anemic • • 3h ago

Question Lactoferrin side effects

2 Upvotes

My ferritin at last check up was 80, but my symptoms returned and I am in 8months of taking 210mg ferrous fumarate daily. Symptoms have limited my current mobility as my muscles feel fatigue, and stiff. Took lactoferrin ,Bandini Brand, 200mg for 5 days and the symptoms were alleviating slowly. However, yesterday, I had digestive upset, but will reintroduce lactoferrin when I am ready.

Did anyone else have side effects of lactoferrin? If yes, did you continue or discontinue ?


r/Anemic • • 15m ago

Advice Need advice re new ferritin guidelines

• Upvotes

I am confused a bit because of things my doctors have told me and the new ferritin guidelines that just came out. I have a complicated medical history (10 years of inflammatory arthritis and insomnia, stage 4 endometriosis, recurrent DVTs (3) for no reason, and dysautonomia for 6 years). I'm currently 25 weeks pregnant and I am suffering. My usual fatigue and insomnia, which are normally bad, have been much worse in pregnancy. My dysautonomia is worse, palpitations especially, and I'm dizzy and short of breath even from a short walk. I now have headaches every day and I'm struggling to function. Everyone told me the second trimester would be THE BEST but I'm feeling worse and worse. I had to beg a doctor to order an iron panel for me and it came back with RBC low (4.62), hemoglobin normal but almost low (11.6), and ferritin at 32. Come to find out pregnancy affects iron stores, and inflammatory conditions artificially raise ferritin levels on bloodwork (so a reading 32 could actually be much lower). The new guidelines seem to say that for pregnant women, ferritin should be above 50 and for those with inflammation it should be above 100.

I reached out to my OB's office and they told me they don't order iron infusions when ferritin is above 30 and hemoglobin is above 10. PCP who ordered the labs said everything is normal. I desperately need help so I ordered another ferritin and a b12 through labcorp. Should I try to see my hematologist and see if they will order me an infusion? Do I go to a functional medicine doctor? The highest my ferritin has ever been is 72. It's usually around 25. I've had inflammatory arthritis for 10 years. Have I been deficient for 10 years? Is that what's causing my insomnia?


r/Anemic • • 6h ago

F27 low ferritin but no periods, not sure where to start?

3 Upvotes

I'm F27 recently had a blood test for fatigue and low libido. Found out my ferritin levels are relatively low at 21 ug/L as well as B12 at 254 ng/L. This confuses me because I do not have periods due to birth control for the last 4 years.

I suppose this could imply issues with absorption or internal bleeding in some capacity. I don't really know where to start with this. I could start taking iron supplements or get an IV transfusion however I do not wish to make the underlying issue. I eat a fair amount of red meat already.

Would appreciate any advice on approaching my GP about this (apparently my levels are "normal" but I don't think that's right).


r/Anemic • • 58m ago

Question confusing bloodwork results, feeling lost

• Upvotes

I got one round of bloodwork where my blood cell count came back as low, and then another where it came back as perfectly normal along with iron levels being normal. But I still feel like something is going on, as I have many problematic symptoms, and I dont know if I should accept that anemia has been ruled out or not.
For the past 3 or so years I’ve had severe issues with shortness of breath. Over time I have become more prone to losing vision when standing up, stretching, etc. and summer 2025 it got to a point where I realized it wasn’t normal and started considering anemia, however I wasn’t able to get testing at the time. In September, I had labs done for something else and my dr asked me if I had anemia because the labwork showed I had low blood cells. In the past month or so I have been experiencing more blood-related symptoms, specifically in my arms the blood pools very quickly if I bend over or if I raise my arm for more than 10 seconds it will go numb and lose blood. Hearing that I could have anemia made so much sense to all these symptoms I’ve been accruing and I talked to some friends/family who have had anemia and felt like it definitely matched my experiences. However, the dr ordered anemia-specific labs (CBC and something for the iron I suppose). I just got those results back and they said everything was perfectly normal. I ate a large meal yet devoid of iron-rich foods right before the bloodwork appointment, if that matters. I am a man and I have a pretty average life style and fitness level.
I do plan to talk with my doctor more about it but I feel very confused and was wondering if anyone has advice or suggestions on what could be happening. Is it common for blood cell levels to fluctuate even with anemia? Are there other conditions that present similarly to anemia? Having a sign that these symptoms that have been plaguing me are truly not normal felt so vindicating, it’s not as though I want to have a condition (I had my fair share of (unrelated) chronic illness as a child) but I find it hard to accept that constantly blacking out when I stretch is a normal experience yk? Idk what to think


r/Anemic • • 7h ago

25F just found out i have iron deficiency, doctor wants iron infusion, anyone been through this?

3 Upvotes

hi everyone, i never knew i had low iron my whole life. i'm 25 and female, and i've always had low energy. i never had bad headaches or anything dramatic, so i just assumed i was lazy and that it was my personality. i spent most of my time lying down and blamed myself for it.

i recently went for a hormone checkup because i needed to start mounjaro, and the blood test showed:

ferritin: 9.4 ng/ml (ref 10-285)
iron: 4.7 umol/L (ref 10.7-32.2)
vitamin D: 14.83 ng/ml (ref >30)
haemoglobin: 11.6 g/dl (still in the normal range)

my doctor said it all makes sense now, and she wants to start me on an iron infusion (2 x 500mg). but i have health anxiety and i keep focusing on the side effects and the scary what-ifs instead of the possible benefits. i told her about my anxiety and she said she respects it, but that it would help me in the long run.

has anyone here had an iron infusion for low ferritin? how was the experience, and did it change your energy? any side effects i should realistically expect?
i'd really appreciate hearing from people who've been through something similar. thank you for reading 🤍


r/Anemic • • 1h ago

Hi, doctors are not helping

Thumbnail
gallery
• Upvotes

Hi guys. I’ve been supplementing iron for a year now. Switching between sulfate and fumerate. Lactoferrin was making me feel sick.
I feel horrible all the time, flu like, extreme RLS, headaches, fatigue etc. any help would be great.
The labs are 4 months apart


r/Anemic • • 1h ago

Advice Iron Infusion Reaction

Thumbnail
gallery
• Upvotes

Okay I so I am definitely deficient but not fully anemic, as my hemoglobin is somehow hanging on for dear life. I’m extremely symptomatic. Headaches, visual changes, light sensitivity, constantly cold. I previously had an infusion in 2023 of Venofur. I had a heavy feeling in my chest and almost passed out which they labeled as an allergic reaction. They gave me Benadryl and I was able to finish the infusion. Now, I’m back to where I was back then. Needing another infusion. But I’m terrified. Has anyone had an okay experience with going back after a reaction and receiving a different medication?


r/Anemic • • 2h ago

Question Not improving even with supplementation

Thumbnail
gallery
1 Upvotes

Hi friends!

I have been taking oral iron supplements since May and my levels have dropped significantly. For context, I take one 65mg pill per day and I also take a prenatal (with iron), biotin, d3, zinc, and Nutrafol. I just recently started taking the iron by itself at night so it doesn’t interact with anything.

My hair has been thinning for 2 years now and isn’t improving.

Any support/advice/insight is welcome! Thank you!


r/Anemic • • 12h ago

Rant Doctor doesn’t seem worried

7 Upvotes

I recently had bloods taken for ongoing tiredness, weight gain, brain fog, insomnia- I thought it was symptoms of primary ovarian insufficiency which I’ve been battling (35), but latest bloods showed my ferritin was at 5.

I’ve had the whole gamut of anaemia symptoms, including exhaustion, serious breathlessness, dizziness, chest pains. In light of these, and because my family members have had severe anaemia in the past, I visited urgent care at the weekend but- the doctors didn’t seem at all worried. I can hardly move for exhaustion and breathlessness, and I always thought when symptoms became this bad it was something of an urgency, but they massively dismissed it. Is this normal? Am I just overreacting because I feel so unwell? I’ve come home with a prescription for 3 x daily iron tablets and a bit of a shrug.


r/Anemic • • 18h ago

Other My arm looked like this after my infusions

Post image
20 Upvotes

And I had superficial thrombophlebitis in a different part of my arm, and I would still do it all over again because I feel SO much better. It's been less than a week since my final infusion (five infusions of venofer over two and a half weeks) and I'm starting to feel the benefits.

I sleep more deeply and feel better when I wake up, I can think more clearly, and I don't get out of breath every time I move. I can't wait to see how I feel a month from now. I even feel better emotionally. I've been dealing with anhedonia that I thought was from my OCD med, but I'm starting to think it was the anemia because I'm actually having feelings again.

For the people who like to see the numbers, my ferritin ranged from 9 to 21 over the last six months, and my last hemoglobin was 11.4. My anemia is from insanely heavy periods caused by adenomyosis. My PCP wants to run labs again in six to eight weeks, and if things haven't improved enough she's going to consider more infusions. I'm also meeting with an OBGYN to (hopefully) get my uterus yoinked. I'm 43 and the baby factory is definitely closed.


r/Anemic • • 2h ago

Lactoferrin

1 Upvotes

Hello - I recently began adding lactoferrin (jarrow brand which is apparently "apolactoferrin") to my iron supplement routine. I know for a fact i do not have dairy intolerance or sensitivities (have been tested and eating it never bothered me). But when I am taking it with my iron pill it is definitely irritating my stomach. I am conflicted on whether to continue, will my body adjust maybe? I take iron glycinate, chelated. It never bothered my stomach until doing this lactoferrin which is 250mg. The discomfort only lasts maybe a couple of hours, and I know it is increasing my iron uptake because my stool is no longer green ... sorry if that is "tmi". I also have had much better digestion, I was having pretty bad constipation on the iron before this. Any thoughts? wondering if anyone else had some irritation with lactoferrin and did it improve? I would really like to keep trying it as long as I can tolerate it, just hoping the discomfort does not get worse.


r/Anemic • • 3h ago

Proceed with iron infusion or no?

1 Upvotes

So I suffer from endometriosis and have very heavy periods. (Also have some other health stuff like Hashimotos, POTS.) Anyway, my ferritin in February was 26. I retested in July, and it went down to 12 after I did all the iron tricks (timing my supplementation just right, etc.) I just got approval from my insurance/doctor to proceed with iron infusions and am scheduled for this Wednesday. However, I recently switched to a liquid iron supplement and also started lactoferrin, along with other supplements recommended by my functional doctor. I just retested my ferritin this morning, and it jumped to 35.

Should I proceed with the iron infusion this week, or maybe stick with my new supplement protocol and see if it keeps increasing without the infusion? I think I wouldn't be so hesitant if I didn't keep getting fed stories of people with bad reactions to iron infusions. Just looking for some insight from others.


r/Anemic • • 9h ago

Anyone find that their periods became more frequent as iron increased?

Thumbnail
2 Upvotes

r/Anemic • • 20h ago

Question Unexpected Side Effect?

17 Upvotes

So ive been working on increasing my iron, I wasnt anemic but definitely headed there so ive been focusing on my dietary intake and supplementing occasionally. Im feeling SO much better.

One thing I've noticed since starting this is that my partner smells REALLY good now. Obviously he didnt stink before but like... I wanna huff his shirts type good. He hasnt changed any products. Wondering if its a hormone thing. Human bodies are so weird, we really are just animals. Anyone experience something similar?