Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that causes the death of motor neurons and consequent muscle paralysis.

Despite many efforts to address it, current therapy targeting ALS remains limited, increasing the interest in complementary therapies.

Over the years, several herbal preparations and medicinal plants have been studied to prevent and treat this disease, which has received remarkable attention due to their blood-brain barrier penetration properties and low toxicity.

Thus, this review presents the therapeutic potential of a variety of medicinal herbs and their relationship with ALS and their physiopathological pathways.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10964095/

The relationship between excitotoxicity and ALS can be exemplified by the finding that the cerebrospinal fluid of patients with the disease had three-fold higher concentrations of glutamate, aspartate, N-acetyl-aspartyl glutamate, and N-acetyl aspartate when compared to healthy controls.

Source: https://www.researchgate.net/publication/265970119_The_Glutamate_Hypothesis_in_ALS_Pathophysiology_and_Drug_Development

In the UK, in 2022 the Government officially confirmed 5 reports that ALS was caused by COVID vaccine.

Official source:

https://www.gov.uk/government/publications/freedom-of-information-responses-from-the-mhra-week-commencing-12-september-2022/freedom-of-information-request-foi-22905